Ex vivo measurements of mucus secretion by colon explants

Jenny K Gustafsson; Henrik Sjövall; Gunnar C Hansson

doi:10.1007/978-1-61779-513-8_14

Ex vivo measurements of mucus secretion by colon explants

Methods Mol Biol. 2012:842:237-43. doi: 10.1007/978-1-61779-513-8_14.

Authors

Jenny K Gustafsson¹, Henrik Sjövall, Gunnar C Hansson

Affiliation

¹ Department of Medical Biochemistry, Mucin Biology Group, University of Gothenburg, Gothenburg, Sweden.

PMID: 22259140
DOI: 10.1007/978-1-61779-513-8_14

Abstract

An explant tissue system for the study and recording of mucus secretion has been developed. Human colon biopsies or tissue from experimental animals are mounted in a horizontal perfusion chamber and the mucus accumulated on the apical side is observed and measured.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Biopsy
Colon / metabolism*
Colonoscopy
Humans
In Vitro Techniques
Mice
Mucus / metabolism*
Rats