Contact allergy to corticosteroids: a frequently missed diagnosis?

J Am Acad Dermatol. 1989 Sep;21(3 Pt 1):538-43. doi: 10.1016/s0190-9622(89)70222-x.

Abstract

Contact allergy to corticosteroids is more prevalent than previously recognized and often goes undetected. Nineteen patients with corticosteroid contact allergy are presented. Sixteen reacted to tixocortol pivalate and also to other corticosteroids, particularly to hydrocortisone, which could explain exacerbations of eczema in these cases. Tixocortol pivalate may be a useful marker for screening patients for contact sensitivity to several corticosteroids.

MeSH terms

  • Adrenal Cortex Hormones / adverse effects*
  • Adult
  • Aged
  • Anti-Inflammatory Agents*
  • Drug Eruptions / diagnosis*
  • Drug Eruptions / etiology
  • Female
  • Humans
  • Hydrocortisone / analogs & derivatives*
  • Male
  • Middle Aged
  • Patch Tests

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • tixocortol pivalate
  • Hydrocortisone