Microwave Ablation Compared to Radiofrequency Ablation for Hepatic Lesions: A Meta-Analysis

Ya Ruth Huo; Guy D Eslick

doi:10.1016/j.jvir.2015.04.004

Microwave Ablation Compared to Radiofrequency Ablation for Hepatic Lesions: A Meta-Analysis

J Vasc Interv Radiol. 2015 Aug;26(8):1139-1146.e2. doi: 10.1016/j.jvir.2015.04.004. Epub 2015 May 28.

Authors

Ya Ruth Huo¹, Guy D Eslick²

Affiliations

¹ Discipline of Surgery, The Whiteley-Martin Research Centre, University of Sydney, Nepean Hospital, Level 3, Clinical Building, P.O. Box 63, Penrith, NSW 2751, Australia.
² Discipline of Surgery, The Whiteley-Martin Research Centre, University of Sydney, Nepean Hospital, Level 3, Clinical Building, P.O. Box 63, Penrith, NSW 2751, Australia.. Electronic address: guy.eslick@sydney.edu.au.

PMID: 26027937
DOI: 10.1016/j.jvir.2015.04.004

Abstract

To evaluate the efficacy and safety of microwave (MW) ablation compared with radiofrequency (RF) ablation for hepatic lesions by using meta-analytic techniques. Overall, 16 studies involving 2,062 patients were included. MW ablation was found to have significantly better 6-year overall survival than RF ablation (odds ratio, 1.64, 95% confidence interval, 1.15-2.35), but this was based on a few articles (n = 3 of 16). MW ablation and RF ablation had similar 1-5-year overall survival, disease-free survival, local recurrence rate, and adverse events. Based on similar safety and efficacy outcomes, either MW ablation or RF ablation may be used for effective local hepatic therapy.

Publication types

Comparative Study
Multicenter Study
Review

MeSH terms

Aged
Catheter Ablation / mortality*
Female
Humans
Incidence
Liver Neoplasms / mortality*
Liver Neoplasms / surgery*
Male
Microwaves / therapeutic use*
Middle Aged
Neoplasm Recurrence, Local / mortality*
Neoplasm Recurrence, Local / prevention & control*
Risk Factors
Survival Rate
Treatment Outcome