A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

Affiliations

• ¹ Medical Department 1, University Hospital Dresden, TU Dresden, Dresden, Germany.
• ² Department of Gastroenterology and Hepatology, University Hospital of Zurich, Zurich, Switzerland.
• ³ Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, Cliniques Universitaires de Bruxelles (CUB) Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
• ⁴ Laboratory of Experimental Gastroenterology, Université Libre de Bruxelles, Brussels, Belgium.
• ⁵ UCL Institute for Liver and Digestive Health, Division of Medicine, Royal Free Campus, University College London, London, UK.
• ⁶ Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK.
• ⁷ Department of Internal Medicine I, University of Bonn, Bonn, Germany.
• ⁸ Section of Hepatology, University Hospital Leipzig, Leipzig, Germany.
• ⁹ Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
• ¹⁰ Psychiatric Health Care Aargau, Psychiatrische Dienste Aargau, Windisch, Switzerland.
• ¹¹ Central Institute of Mental Health, University of Heidelberg, Faculty of Medicine Mannheim, Mannheim, Germany.
• ¹² Department of Internal Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
• ¹³ Institute of Epidemiology and Biobank PopGen, Christian Albrechts University Kiel, Kiel, Germany.
• ¹⁴ Psychiatric Hospital, Ludwig Maximilians University, Munich, Germany.
• ¹⁵ Department of Visceral Surgery and Medicine, Inselspital Bern, Bern, Switzerland.
• ¹⁶ Department of Internal Medicine, Hospital Oberndorf, Teaching Hospital of the Paracelsus Private University of Salzburg, Salzburg, Austria.
• ¹⁷ Centre Hospitalier Le Domaine, Université Libre de Bruxelles, Braine-l'Alleud, Belgium.
• ¹⁸ Department of Gastroenterology, University Hospital Frankfurt, Frankfurt, Germany.
• ¹⁹ Department of Medicine II, Saarland University Hospital, Homburg, Germany.
• ²⁰ Service d'Hépato-Gastroentérologie, Hôpital de Jolimont, Haine-Saint-Paul, Belgium.
• ²¹ Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.
• ²² Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
• ²³ Department of Internal Medicine A, University Medicine Greifswald, Greifswald, Germany.
• ²⁴ Department of Clinical Toxicology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
• ²⁵ Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
• ²⁶ Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
• ²⁷ Institute of Human Genetics, University of Bonn, Bonn, Germany.
• ²⁸ Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.
• ²⁹ Cologne Center for Genomics, University of Cologne, Cologne, Germany.
• ³⁰ Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.
• ³¹ Fritz Lipmann Institute of Age Research (FLI), Jena, Germany.
• ³² Department of Internal Medicine 1, University Hospital Erlangen, Erlangen, Germany.
• ³³ Department of Internal Medicine 1, University Hospital Regensburg, Regensburg, Germany.