Erythropoietic protoporphyria exacerbated by oral iron therapy

Br J Dermatol. 1988 Jul;119(1):63-6. doi: 10.1111/j.1365-2133.1988.tb07102.x.

Abstract

Four patients with erythropoietic protoporphyria (EPP) are reported, in whom oral iron produced clear-cut clinical and biochemical deterioration. This suggests that there are two biochemically and genetically distinct sub-groups of EPP patients distinguished by their dramatically different response to oral iron.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anemia, Hypochromic / drug therapy
  • Anemia, Hypochromic / etiology
  • Female
  • Ferritins / blood
  • Humans
  • Iron / adverse effects*
  • Iron / blood
  • Photosensitivity Disorders / blood
  • Photosensitivity Disorders / chemically induced*
  • Porphyrias / complications
  • Protoporphyrins / blood
  • Skin Diseases / complications

Substances

  • Protoporphyrins
  • Ferritins
  • Iron