Abstract
Intravenously injected cholecystokinin octapeptide (CCK-8) (5-20/micrograms/kg) and caerulein (1.25-10/micrograms/kg) caused a prompt, dose-dependent and sustained improvement in blood pressure, pulse amplitude and survival in rats subjected to otherwise invariably fatal hemorrhagic shock.
MeSH terms
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Animals
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Blood Pressure / drug effects
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Ceruletide / administration & dosage
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Ceruletide / pharmacology
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Ceruletide / therapeutic use*
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Female
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Injections, Intravenous
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Rats
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Rats, Inbred Strains
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Shock, Hemorrhagic / drug therapy*
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Sincalide / administration & dosage
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Sincalide / pharmacology
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Sincalide / therapeutic use*