Studies on the mechanism of formation of 5-mercapto-1-methyl-4-nitroimidazole, a metabolite of the immunosuppressive drug azathioprine

Biochem Pharmacol. 1974 Jul 1;23(13):1891-901. doi: 10.1016/0006-2952(74)90198-1.
No abstract available

MeSH terms

  • Animals
  • Azathioprine / metabolism*
  • Humans
  • Imidazoles / chemical synthesis
  • Imidazoles / metabolism*
  • Imidazoles / urine
  • Male
  • Mice
  • Nitro Compounds / chemical synthesis
  • Nitro Compounds / metabolism*
  • Nitro Compounds / urine
  • Spectrophotometry
  • Spectrophotometry, Ultraviolet
  • Sulfhydryl Compounds / urine
  • Time Factors

Substances

  • Imidazoles
  • Nitro Compounds
  • Sulfhydryl Compounds
  • Azathioprine