Abstract
We have reviewed 66 cases of antibiotic-associated colitis since March 1975, which have been associated with a 27 per cent mortality. We believe antibiotics may predispose patients to this condition which is caused by a toxin produced by Clostridium difficile. Although the disease is rare, it is more common than previously reported. The presentation, methods of diagnosis and treatment are discussed.
MeSH terms
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Adolescent
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Adult
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Aged
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Anti-Bacterial Agents / adverse effects*
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Bacterial Toxins / analysis
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Clostridium
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Enterocolitis, Pseudomembranous / chemically induced*
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Enterocolitis, Pseudomembranous / drug therapy
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Enterocolitis, Pseudomembranous / mortality
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Feces / analysis
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Female
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Humans
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Male
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Middle Aged
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Vancomycin / therapeutic use
Substances
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Anti-Bacterial Agents
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Bacterial Toxins
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Vancomycin