Abstract
The collectins are proteins with collagen tails and globular lectin domains that appear to play an important role in mammalian first line host defense. Recent insights have clarified the structural basis of ligand recognition, the interactions of collectins with complement cascades, and the association with disease susceptibility.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Carrier Proteins / chemistry
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Carrier Proteins / genetics
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Carrier Proteins / immunology*
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Cattle
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Collectins
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Complement Pathway, Classical
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Disease Susceptibility / ethnology
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Disease Susceptibility / immunology
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Disease Susceptibility / metabolism
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Dogs
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Humans
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Immunity, Innate*
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Ligands
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Mannose-Binding Lectins
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Mice
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Models, Molecular
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Molecular Structure
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Rabbits
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Rats
Substances
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Carrier Proteins
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Collectins
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Ligands
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Mannose-Binding Lectins