Abstract
This report describes a family in which the father and three children had a sliding hiatus hernia. In each case there was gastro-oesophageal reflux from the neonatal period which proved unresponsive to medical therapy, ultimately requiring anti-reflux surgery. The trait in this family supports an autosomal dominant genetic component to the infant hiatus hernia.
MeSH terms
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Chromosome Aberrations / genetics*
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Chromosome Disorders
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Esophagitis, Peptic / diagnosis
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Esophagitis, Peptic / genetics
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Esophagitis, Peptic / surgery
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Female
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Fundoplication
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Gastroesophageal Reflux / diagnosis
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Gastroesophageal Reflux / genetics*
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Gastroesophageal Reflux / surgery
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Genes, Dominant / genetics*
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Hernia, Hiatal / diagnosis
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Hernia, Hiatal / genetics*
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Hernia, Hiatal / surgery
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Humans
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Infant
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Infant, Newborn
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Male
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Postoperative Complications / etiology
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Postoperative Complications / surgery
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Pyloric Antrum / surgery
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Reoperation