Familial hiatus hernia and gastro-oesophageal reflux

Eur J Pediatr Surg. 1996 Jun;6(3):175-6. doi: 10.1055/s-2008-1066501.

Abstract

This report describes a family in which the father and three children had a sliding hiatus hernia. In each case there was gastro-oesophageal reflux from the neonatal period which proved unresponsive to medical therapy, ultimately requiring anti-reflux surgery. The trait in this family supports an autosomal dominant genetic component to the infant hiatus hernia.

Publication types

  • Case Reports

MeSH terms

  • Chromosome Aberrations / genetics*
  • Chromosome Disorders
  • Esophagitis, Peptic / diagnosis
  • Esophagitis, Peptic / genetics
  • Esophagitis, Peptic / surgery
  • Female
  • Fundoplication
  • Gastroesophageal Reflux / diagnosis
  • Gastroesophageal Reflux / genetics*
  • Gastroesophageal Reflux / surgery
  • Genes, Dominant / genetics*
  • Hernia, Hiatal / diagnosis
  • Hernia, Hiatal / genetics*
  • Hernia, Hiatal / surgery
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Postoperative Complications / etiology
  • Postoperative Complications / surgery
  • Pyloric Antrum / surgery
  • Reoperation