Somatostatin in the treatment of gastrointestinal bleeding caused by angiodysplasia

Scand J Gastroenterol. 1996 Oct;31(10):1037-9. doi: 10.3109/00365529609003126.

Abstract

Background: Bleeding due to gastrointestinal angiodysplasia is occasionally very difficult to treat by conventional means.

Methods: A 37-year-old woman with recurrent anemia caused by angiodysplasia was treated with a somatostatin analogue, given at a dose of 100 micrograms subcutaneously twice daily.

Results: After 26 months of treatment the patient was without any signs or symptoms of bleeding from her gastrointestinal angiodysplasia.

Conclusions: Somatostatin may be efficacious in the treatment of gastrointestinal bleeding due to angiodysplasia. Further investigation is needed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiodysplasia / complications*
  • Female
  • Follow-Up Studies
  • Gastrointestinal Hemorrhage* / drug therapy
  • Gastrointestinal Hemorrhage* / etiology
  • Hemoglobins / analysis*
  • Hormone Antagonists / administration & dosage
  • Hormone Antagonists / therapeutic use*
  • Humans
  • Injections, Subcutaneous
  • Somatostatin / administration & dosage
  • Somatostatin / therapeutic use*
  • Time Factors

Substances

  • Hemoglobins
  • Hormone Antagonists
  • Somatostatin