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Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites.
Button JE, Cosetta CM, Reens AL, Brooker SL, Rowan-Nash AD, Lavin RC, Saur R, Zheng S, Autran CA, Lee ML, Sun AK, Alousi AM, Peterson CB, Koh AY, Rechtman DJ, Jenq RR, McKenzie GJ. Button JE, et al. Among authors: autran ca. Cell Host Microbe. 2023 Sep 13;31(9):1523-1538.e10. doi: 10.1016/j.chom.2023.08.004. Epub 2023 Aug 31. Cell Host Microbe. 2023. PMID: 37657443
Human milk oligosaccharides inhibit growth of group B Streptococcus.
Lin AE, Autran CA, Szyszka A, Escajadillo T, Huang M, Godula K, Prudden AR, Boons GJ, Lewis AL, Doran KS, Nizet V, Bode L. Lin AE, et al. Among authors: autran ca. J Biol Chem. 2017 Jul 7;292(27):11243-11249. doi: 10.1074/jbc.M117.789974. Epub 2017 Apr 17. J Biol Chem. 2017. PMID: 28416607 Free PMC article.
Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection.
Ramani S, Stewart CJ, Laucirica DR, Ajami NJ, Robertson B, Autran CA, Shinge D, Rani S, Anandan S, Hu L, Ferreon JC, Kuruvilla KA, Petrosino JF, Venkataram Prasad BV, Bode L, Kang G, Estes MK. Ramani S, et al. Among authors: autran ca. Nat Commun. 2018 Nov 27;9(1):5010. doi: 10.1038/s41467-018-07476-4. Nat Commun. 2018. PMID: 30479342 Free PMC article.
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics.
Button JE, Autran CA, Reens AL, Cosetta CM, Smriga S, Ericson M, Pierce JV, Cook DN, Lee ML, Sun AK, Alousi AM, Koh AY, Rechtman DJ, Jenq RR, McKenzie GJ. Button JE, et al. Among authors: autran ca. Cell Host Microbe. 2022 May 11;30(5):712-725.e7. doi: 10.1016/j.chom.2022.04.001. Epub 2022 May 2. Cell Host Microbe. 2022. PMID: 35504279 Free article.
12 results