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PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells.
Mangiapane LR, Nicotra A, Turdo A, Gaggianesi M, Bianca P, Di Franco S, Sardina DS, Veschi V, Signore M, Beyes S, Fagnocchi L, Fiori ME, Bongiorno MR, Lo Iacono M, Pillitteri I, Ganduscio G, Gulotta G, Medema JP, Zippo A, Todaro M, De Maria R, Stassi G. Mangiapane LR, et al. Among authors: sardina ds. Gut. 2022 Jan;71(1):119-128. doi: 10.1136/gutjnl-2020-323553. Epub 2021 Jan 12. Gut. 2022. PMID: 33436496 Free PMC article.
Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery.
Di Franco S, Bianca P, Sardina DS, Turdo A, Gaggianesi M, Veschi V, Nicotra A, Mangiapane LR, Lo Iacono M, Pillitteri I, van Hooff S, Martorana F, Motta G, Gulotta E, Lentini VL, Martorana E, Fiori ME, Vieni S, Bongiorno MR, Giannone G, Giuffrida D, Memeo L, Colarossi L, Mare M, Vigneri P, Todaro M, De Maria R, Medema JP, Stassi G. Di Franco S, et al. Among authors: sardina ds. Nat Commun. 2021 Aug 18;12(1):5006. doi: 10.1038/s41467-021-25333-9. Nat Commun. 2021. PMID: 34408135 Free PMC article.
Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant.
Veschi V, Mangiapane LR, Nicotra A, Di Franco S, Scavo E, Apuzzo T, Sardina DS, Fiori M, Benfante A, Colorito ML, Cocorullo G, Giuliante F, Cipolla C, Pistone G, Bongiorno MR, Rizzo A, Tate CM, Wu X, Rowlinson S, Stancato LF, Todaro M, De Maria R, Stassi G. Veschi V, et al. Among authors: sardina ds. Oncogene. 2020 Jan;39(5):987-1003. doi: 10.1038/s41388-019-1047-4. Epub 2019 Oct 7. Oncogene. 2020. PMID: 31591478 Free PMC article.