Background Turcot's syndrome is characterized clinically by the concurrence of a primary
brain tumor and multiple colorectal adenomas. We attempted to define the syndrome at the …

Background & Aims: The Peutz–Jeghers syndrome (PJS) is an autosomal dominant
polyposis disorder with increased risk of multiple cancers, but literature estimates of risk …

Background For many years anecdotal case reports have suggested that pancreatic cancer
aggregates in some families. Methods Two recent advances have established that this is in …

Individuals with a family history of pancreatic cancer have an increased risk of developing
pancreatic cancer. Quantification of this risk provides a rational basis for cancer risk …

Adenomas with potential for malignancy occur frequently in the upper gastrointestinal tract of
patients with familial adenomatous polyposis. However, an assessment of relative risk of …

It has been estimated that familial aggregation and genetic susceptibility play a role in as
many as 10% of patients with pancreatic cancer (PC). The quantified prospective risk of PC …

Familial adenomatous polyposis has been associated with several extraintestinal cancers,
but the relative and absolute risks of these malignancies have not been determined …

Background: Juvenile polyposis (JP) is an autosomal-dominant syndrome characterised by
the development of hamartomatous gastrointestinal polyps and is associated with colorectal …

The present study intends to identify factors that predict postoperative clinical outcome in
patients with gangliogliomas (GG) and dysembryoplastic neuroepithelial tumors (DNT). We …

7 6 6 Clinical and laboratory observations The Journal of Pediatrics November 1991 tional,
an exceedingly long time would be required for a single center to accrue a large-enough …