Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
We present a genome-wide association study of ileal Crohn disease and two independent
replication studies that identify several new regions of association to Crohn disease …
replication studies that identify several new regions of association to Crohn disease …
Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
Ulcerative colitis is a chronic inflammatory disease of the colon that presents as diarrhea
and gastrointestinal bleeding. We performed a genome-wide association study using DNA …
and gastrointestinal bleeding. We performed a genome-wide association study using DNA …
Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses
GY Melmed, AF Ippoliti, KA Papadakis… - Official journal of the …, 2006 - journals.lww.com
BACKGROUND Patients with chronic, immune-mediated conditions such as inflammatory
bowel disease (IBD) are often treated with long-term immunosuppressive therapies …
bowel disease (IBD) are often treated with long-term immunosuppressive therapies …
Immunosuppression impairs response to pneumococcal polysaccharide vaccination in patients with inflammatory bowel disease
OBJECTIVES: The treatment of inflammatory bowel disease (IBD) often includes
immunosuppressive medications, which may increase the risk of vaccine-preventable …
immunosuppressive medications, which may increase the risk of vaccine-preventable …
Esophagitis in scleroderma: prevalence and risk factors
BJ Zamost, J Hirschberg, AF Ippoliti, DE Furst… - Gastroenterology, 1987 - Elsevier
Of 53 patients with scleroderma (43 women and 10 men) evaluated by esophagoscopy and
biopsy, 32 (60%) had erosive esophagitis. Symptoms of heart-burn and dysphagia were …
biopsy, 32 (60%) had erosive esophagitis. Symptoms of heart-burn and dysphagia were …
Two doses of omeprazole versus placebo in symptomatic erosive esophagitis: the US Multicenter Study
SJ Sontag, BI Hirschowitz, S Holt, MG Robinson… - Gastroenterology, 1992 - Elsevier
Two hundred thirty patients with reflux symptoms and endoscopically proven erosive
esophagitis were enrolled from 15 US centers into a randomized, double-blind, dose …
esophagitis were enrolled from 15 US centers into a randomized, double-blind, dose …
Predicting a change in diagnosis from ulcerative colitis to Crohn's disease: a nested, case-control study
GY Melmed, R Elashoff, GC Chen, I Nastaskin… - Clinical …, 2007 - Elsevier
Background & Aims: Some patients diagnosed with UC undergo a change in diagnosis to
CD. Identification of predictors of a diagnostic change could potentially impact the …
CD. Identification of predictors of a diagnostic change could potentially impact the …
High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females
M Saruta, SR Targan, L Mei, AF Ippoliti… - Inflammatory bowel …, 2009 - academic.oup.com
Background TNF-α and IL-1 have been associated with mucosal inflammation in both
Crohn's disease (CD) and ulcerative colitis (UC). Innate immune defects have been …
Crohn's disease (CD) and ulcerative colitis (UC). Innate immune defects have been …
The effect of various forms of milk on gastric-acid secretion: Studies in patients with duodenal ulcer and normal subjects
AF Ippoliti, V MAXWELL… - Annals of Internal …, 1976 - acpjournals.org
Milk is commonly recommended as therapy for patients with peptic ulcer. The purpose of this
study was to examine the effect of various forms of milk and 0.15 M NaCl (control) on gastric …
study was to examine the effect of various forms of milk and 0.15 M NaCl (control) on gastric …
Esophageal motility abnormalities in cirrhotic patients before and after endoscopic variceal treatment.
R Fass, O Landau, TOG Kovacs… - American Journal of …, 1997 - search.ebscohost.com
Esophageal motility abnormalities in patients treated endoscopically for variceal
hemorrhage are rarely studied and usually are not addressed in the clinical setting …
hemorrhage are rarely studied and usually are not addressed in the clinical setting …