Pro-hepcidin: expression and cell specific localisation in the liver and its regulation in hereditary haemochromatosis, chronic renal insufficiency, and renal anaemia

H Kulaksiz, SG Gehrke, A Janetzko, D Rost, T Bruckner… - Gut, 2004 - gut.bmj.com
Background and aims: The hepatic peptide hormone hepcidin, which has recently been
isolated from human plasma and urine, is thought to be a central regulator of iron …

[HTML][HTML] The iron-regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney

…, SG Gehrke, D Rost, A Janetzko… - Journal of …, 2005 - joe.bioscientifica.com
It is generally accepted that iron homeostasis is mainly controlled in the gastrointestinal tract
by absorption of dietary iron. However, recent studies have shown that the kidneys are also …

Isolation and characterization of developmentally regulated chondroitin sulfate and chondroitin/keratan sulfate proteoglycans of brain identified with monoclonal …

U Rauch, P Gao, A Janetzko, A Flaccus… - Journal of Biological …, 1991 - ASBMB
A panel of monoclonal antibodies prepared to the chondroitin sulfate proteoglycans of rat
brain was used for their immunocytochemical localization and isolation of individual …

A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic …

M Fäcke, A Janetzko, RL Shoeman… - Journal of …, 1993 - Am Soc Microbiol
Morphogenesis of retroviruses involves assembly of the structural Gag and Gag-Pol
polyproteins with subsequent budding of the virus particle from the plasma membrane and …

Validation of connective tissue growth factor (CTGF/CCN2) and its gene polymorphisms as noninvasive biomarkers for the assessment of liver fibrosis

…, HW Zimmermann, B Lahme, A Janetzko… - Journal of viral …, 2009 - Wiley Online Library
Clinical and experimental studies have demonstrated that connective‐tissue growth factor
(CTGF) expression is increased in fibrotic human liver and experimental animal models of …

DNA-mediated transport of the intermediate filament protein vimentin into the nucleus of cultured cells

R Hartig, RL Shoeman, A Janetzko… - Journal of Cell …, 1998 - journals.biologists.com
ABSTRACT A number of characteristic properties of intermediate filament (IF) proteins, such
as nucleic acid-binding activity, affinity for histones and structural relatedness to transcription …

Association of the HNK-1 epitope with 5′-nucleotidase from Torpedo marmorata (electric ray) electric organ

…, HJ Kowalewski, H Zimmermann, A Janetzko… - Biochemical …, 1991 - portlandpress.com
5′-Nucleotidase isolated from the electric organ of the electric ray (Torpedo marmorata)
has a molecular mass of 62 kDa and, on two-dimensional electrophoresis, separates into up …

Structural elements the amino-terminal head domain of vimentin essential for intermediate filament formation in vivo and in vitro

M Beuttenmüller, M Chen, A Janetzko, S Kühn… - Experimental cell …, 1994 - Elsevier
The biological functions of the non-α-helical, N-and C-terminal head and tail domains of
intermediate filament (IF) proteins are still ill-defined. Previously, it has been shown that the …

Altered angiogenesis in preeclampsia: evaluation of a new test system for measuring placental growth factor

…, C Birdir, R Callies, U Kuhn, A Gellhaus, A Janetzko… - 2007 - degruyter.com
Background: Decreased concentrations of the circulating angiogenic factors, free placental
growth factor (PLGF) and free vascular endothelial growth factor (VEGF), and increased …

A novel monoclonal antibody immunoassay for the detection of human serum hepcidin

P Schwarz, P Strnad, G von Figura, A Janetzko… - Journal of …, 2011 - Springer
Background Hepcidin is a liver-derived peptide hormone regulating iron metabolism.
Changes in the expression of hepcidin are known to be the key pathogenic factors in …