User profiles for "author:A Maitra"

ANIRBAN MAITRA

Professor of Translational Molecular Pathology, UT MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 120558

An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

…, DS Longnecker, J Luttges, A Maitra… - The American journal …, 2004 - journals.lww.com
Invasive pancreatic ductal adenocarcinoma is an almost uniformly fatal disease. Several
distinct noninvasive precursor lesions can give rise to invasive adenocarcinoma of the …

Pancreatic cancer stroma: an update on therapeutic targeting strategies

AN Hosein, RA Brekken, A Maitra - Nature reviews Gastroenterology & …, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related mortality in
the Western world with limited therapeutic options and dismal long-term survival. The …

Pancreatic cancer

A Maitra, RH Hruban - Annu. Rev. Pathol. Mech. Dis., 2008 - annualreviews.org
The past two decades have witnessed an explosion in our understanding of pancreatic
cancer, and it is now clear that pancreatic cancer is a disease of inherited (germ-line) and …

Whole genomes redefine the mutational landscape of pancreatic cancer

…, R Grützmann, D Aust, RH Hruban, A Maitra… - Nature, 2015 - nature.com
Pancreatic cancer remains one of the most lethal of malignancies and a major health
burden. We performed whole-genome sequencing and copy number variation (CNV) …

Genomic analyses identify molecular subtypes of pancreatic cancer

…, F Duthie, K Oien, J Hair, R Grützmann, A Maitra… - Nature, 2016 - nature.com
Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32
recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH …

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

…, SD Leach, AP Klein, EM Jaffee, M Goggins, A Maitra… - science, 2008 - science.org
There are currently few therapeutic options for patients with pancreatic cancer, and new
insights into the pathogenesis of this lethal disease are urgently needed. Toward this end …

A draft map of the human proteome

…, JT Schroeder, R Sirdeshmukh, A Maitra… - Nature, 2014 - nature.com
The availability of human genome sequence has transformed biomedical research over the
past decade. However, an equivalent map for the human proteome with direct …

[PDF][PDF] Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

SR Hingorani, EF Petricoin, A Maitra, V Rajapakse… - Cancer cell, 2003 - cell.com
To evaluate the role of oncogenic RAS mutations in pancreatic tumorigenesis, we directed
endogenous expression of KRAS G12D to progenitor cells of the mouse pancreas. We find …

[PDF][PDF] Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

…, CJ Lowenstein, DE Arking, MA Beer, A Maitra… - Molecular cell, 2007 - cell.com
The p53 tumor suppressor protein is a critical regulator of the cellular response to cancer-
initiating insults such as genotoxic stress. In this report, we demonstrate that microRNAs …

[HTML][HTML] Elucidation of a universal size-control mechanism in Drosophila and mammals

…, SA Comerford, MF Gayyed, RA Anders, A Maitra… - Cell, 2007 - cell.com
Coordination of cell proliferation and cell death is essential to attain proper organ size
during development and for maintaining tissue homeostasis throughout postnatal life. In …