[HTML][HTML] The Brazilian Zika virus strain causes birth defects in experimental models
Zika virus (ZIKV) is an arbovirus belonging to the genus Flavivirus (family Flaviviridae) and
was first described in 1947 in Uganda following blood analyses of sentinel Rhesus …
was first described in 1947 in Uganda following blood analyses of sentinel Rhesus …
Protective effect of metronidazole on uncoupling mitochondrial oxidative phosphorylation induced by NSAID: a new mechanism
BACKGROUND The pathogenesis of non-steroidal anti-inflammatory drug (NSAID)
enteropathy is complex. It involves uncoupling of mitochondrial oxidative phosphorylation …
enteropathy is complex. It involves uncoupling of mitochondrial oxidative phosphorylation …
Brain PET amyloid and neurodegeneration biomarkers in the context of the 2018 NIA-AA research framework: an individual approach exploring clinical-biomarker …
AM Coutinho, GF Busatto, FH de Gobbi Porto… - European journal of …, 2020 - Springer
Abstract Purpose [18 F] FDG-PET and [11 C] PIB-PET are validated as neurodegeneration
and amyloid biomarkers of Alzheimer's disease (AD). We used a PET staging system based …
and amyloid biomarkers of Alzheimer's disease (AD). We used a PET staging system based …
[HTML][HTML] Topography of 11C-Pittsburgh compound B uptake in Alzheimer's disease: a voxel-based investigation of cortical and white matter regions
Objective: To compare results of positron emission tomography (PET) with carbon-11-
labeled Pittsburgh compound B (11C-PIB) obtained with cerebellar or global brain uptake …
labeled Pittsburgh compound B (11C-PIB) obtained with cerebellar or global brain uptake …
High‐intensity interval training slows down tumor progression in mice bearing Lewis lung carcinoma
Background We aimed to determine whether a short‐term high‐intensity interval training
(HIIT) protocol could counteract tumor progression in an experimental model of lung cancer …
(HIIT) protocol could counteract tumor progression in an experimental model of lung cancer …
In vivo imaging evidence of poor cognitive resilience to Alzheimer's disease pathology in subjects with very low cognitive reserve from a low‐middle income …
GF Busatto, FH de Gobbi Porto, DP Faria… - Alzheimer's & …, 2020 - Wiley Online Library
INTRODUCTION: Reduced cognitive reserve (CR) due to very low educational (VLE) levels
may influence high dementia rates in low‐middle income environments, leading to …
may influence high dementia rates in low‐middle income environments, leading to …
[11C] PIB PET imaging can detect white and grey matter demyelination in a non-human primate model of progressive multiple sclerosis
RHF Carvalho, CC Real, S Cinini, AT Garcez… - Multiple Sclerosis and …, 2019 - Elsevier
Background Multiple sclerosis (MS) is a demyelinating and inflammatory disease of the
central nervous system. Its diagnosis is clinical, often confirmed by magnetic resonance …
central nervous system. Its diagnosis is clinical, often confirmed by magnetic resonance …
The contributions of dipeptidyl peptidase IV to inflammation in heart failure
T de Almeida Salles, C Zogbi… - American Journal …, 2016 - journals.physiology.org
Circulating dipeptidyl peptidase IV (DPPIV) activity correlates with cardiac dysfunction in
humans and experimental heart failure (HF) models. Similarly, inflammatory markers are …
humans and experimental heart failure (HF) models. Similarly, inflammatory markers are …
[HTML][HTML] Evaluation of 10-minute post-injection 11C-PiB PET and its correlation with 18F-FDG PET in older adults who are cognitively healthy, mildly impaired, or with …
Objective: Positron emission tomography (PET) allows in vivo evaluation of molecular
targets in neurodegenerative diseases, such as Alzheimer's disease. Mild cognitive …
targets in neurodegenerative diseases, such as Alzheimer's disease. Mild cognitive …
Evaluation of GX1 and RGD-GX1 peptides as new radiotracers for angiogenesis evaluation in experimental glioma models
ÉA de Oliveira, BL Faintuch, RC Targino, AM Moro… - Amino Acids, 2016 - Springer
Gliomas are the most common type among all central nervous system tumors. The
aggressiveness of gliomas is correlated with the level of angiogenesis and is often …
aggressiveness of gliomas is correlated with the level of angiogenesis and is often …