Objective The nature of the tumour-infiltrating leucocytes (TILs) is known to impact clinical
outcome in carcinomas, including hepatocellular carcinoma (HCC). However, the role of …

Characterization of the T cell response in individuals who recover from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical to understanding its …

Macrophages are ubiquitous cells physiologically involved in a variety of processes
including pathogen destruction, inflammation, tissue repair and remodeling. They have a …

Objective Hepatocellular carcinoma (HCC) is a heterogeneous disease with poor prognosis
and limited methods for predicting patient survival. The nature of the immune cells that …

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is an aggressive malignancy with
few treatment options. As the status of the tumour immune microenvironment can affect …

T-cell infiltration is known to impact tumor growth and is associated with cancer patient
survival. However, the molecular cues that favor T-cell infiltration remain largely undefined …

There is a growing concern that ongoing evolution of SARS-CoV-2 could lead to variants of
concern (VOC) that are capable of avoiding some or all of the multifaceted immune …

Background & Aims Immune checkpoint inhibitors are effective in the treatment of some
hepatocellular carcinomas (HCCs), but these tumors do not always respond to inhibitors of …

This study examined whether CD8+ T-cell responses from coronavirus disease 2019
convalescent individuals (n= 30) potentially maintain recognition of the major severe acute …

Abstract Background Southeast Asian populations are increasingly affected by allergic
airway diseases. Etiology and specific causes, however, are still unknown. The aim of this …