Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …

Obesity is currently the most extended metabolic disturbance worldwide favoring the
development of cardiometabolic alterations such as type 2 diabetes, hypertension, and …

Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …

OBJECTIVE To assess the predictive capacity of a recently described equation that we have
termed CUN-BAE (Clínica Universidad de Navarra-Body Adiposity Estimator) based on BMI …

Context: Obesity acts as a cardiovascular risk factor by mechanisms that are not fully
understood. Osteopontin (OPN) is a proinflammatory mediator involved in tissue remodeling …

Objective: Glycerol constitutes an important metabolite for the control of lipid accumulation
and glucose homeostasis. The impact of obesity and obesity-associated type 2 diabetes as …

Background Obesity and obesity-associated type 2 diabetes mellitus (T2DM) are frequently
related to a low-grade chronic inflammatory state, which increases the risk of developing …

Context: Betatrophin is a secreted protein recently involved in β-cell replication with a
potential role in type 2 diabetes mellitus (T2D). Objective: The aim of the present study was …

Obesity favors the development of cardiometabolic alterations such as type 2 diabetes (T2D)
and the metabolic syndrome (MS). Obesity and the MS are distinguished by an increase in …

The aim of the present work was to study whether the leptin-adiponectin axis may have a
pathophysiological role in the increased systemic inflammation and oxidative stress …