User profiles for "author:Ana Beloqui"

Ana Beloqui

Université catholique de Louvain
Verified email at uclouvain.be
Cited by 2898

Nanostructured lipid carriers: Promising drug delivery systems for future clinics

A Beloqui, MÁ Solinís, A Rodríguez-Gascón… - … , biology and medicine, 2016 - Elsevier
During the past decade, the number of studies describing nanostructured lipid carriers
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …

Metagenomics for mining new genetic resources of microbial communities

M Ferrer, A Beloqui, KN Timmis… - Journal of molecular …, 2009 - karger.com
Recent progress has revealed that the capture of genetic resources of complex microbial
communities in metagenome libraries allows the discovery of a richness of new enzymatic …

Mining enzymes from extreme environments

M Ferrer, O Golyshina, A Beloqui… - Current opinion in …, 2007 - Elsevier
Current advances in metagenomics have revolutionized the research in fields of microbial
ecology and biotechnology, enabling not only a glimpse into the uncultured microbial …

Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier

A Beloqui, MÁ Solinís, AR Gascón… - Journal of Controlled …, 2013 - Elsevier
The aims of this work were (i) to evaluate the potential of nanostructured lipid carriers
(NLCs) as a tool to enhance the oral bioavailability of poorly soluble compounds using …

[HTML][HTML] Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic …

A Beloqui, M Pita, J Polaina, A Martínez-Arias… - Journal of Biological …, 2006 - ASBMB
RL5, a gene coding for a novel polyphenol oxidase, was identified through activity screening
of a metagenome expression library from bovine rumen microflora. Characterization of the …

pH-sensitive nanoparticles for colonic delivery of curcumin in inflammatory bowel disease

A Beloqui, R Coco, PB Memvanga, B Ucakar… - International journal of …, 2014 - Elsevier
Nano-scaled particles have been found to preferentially accumulate in inflamed regions.
Local delivery of anti-inflammatory drugs loaded in nanoparticles to the inflamed colonic site …

Surface modification of lipid-based nanoparticles

Y Xu, T Fourniols, Y Labrak, V Préat, A Beloqui… - ACS …, 2022 - ACS Publications
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

[HTML][HTML] Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery

AB Buya, A Beloqui, PB Memvanga, V Préat - Pharmaceutics, 2020 - mdpi.com
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers

Y Xu, N Shrestha, V Préat, A Beloqui - Advanced Drug Delivery Reviews, 2021 - Elsevier
Oral administration is the most commonly used route for drug delivery owing to its cost-
effectiveness, ease of administration, and high patient compliance. However, the absorption …

Metagenomics approaches in systems microbiology

JM Vieites, ME Guazzaroni, A Beloqui… - FEMS microbiology …, 2008 - academic.oup.com
The world of microorganisms comprises a vast diversity of live organisms, each with its
individual set of genes, cellular components and metabolic reactions that interact within the …