[HTML][HTML] Pexophagy: the selective degradation of peroxisomes
A Till, R Lakhani, SF Burnett, S Subramani - International journal of cell …, 2012 - hindawi.com
Peroxisomes are single-membrane-bounded organelles present in the majority of eukaryotic
cells. Despite the existence of great diversity among different species, cell types, and under …
cells. Despite the existence of great diversity among different species, cell types, and under …
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
We performed a genome-wide association study of 19,779 nonsynonymous SNPs in 735
individuals with Crohn disease and 368 controls. A total of 7,159 of these SNPs were …
individuals with Crohn disease and 368 controls. A total of 7,159 of these SNPs were …
G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation
C Sina, O Gavrilova, M Förster, A Till… - The Journal of …, 2009 - journals.aai.org
Molecular danger signals attract neutrophilic granulocytes (polymorphonuclear leukocytes
(PMNs)) to sites of infection. The G protein-coupled receptor (GPR) 43 recognizes …
(PMNs)) to sites of infection. The G protein-coupled receptor (GPR) 43 recognizes …
[HTML][HTML] NOD-like receptors and human diseases
P Rosenstiel, A Till, S Schreiber - Microbes and infection, 2007 - Elsevier
NOD-like receptors are cytosolic proteins that contain a central nucleotide-binding
oligomerization domain (NACHT), an N-terminal effector-binding domain and C-terminal …
oligomerization domain (NACHT), an N-terminal effector-binding domain and C-terminal …
[HTML][HTML] Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis
SJ Kim, M Khan, J Quan, A Till, S Subramani… - PLoS …, 2013 - journals.plos.org
Human hepatitis B virus (HBV) causes chronic hepatitis and is associated with the
development of hepatocellular carcinoma. HBV infection alters mitochondrial metabolism …
development of hepatocellular carcinoma. HBV infection alters mitochondrial metabolism …
The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses
S Kuenzel, A Till, M Winkler, R Häsler… - The journal of …, 2010 - journals.aai.org
Nucleotide-binding oligomerization domain-like receptors (NLRs) are a group of intracellular
proteins that mediate recognition of pathogen-associated molecular patterns or other …
proteins that mediate recognition of pathogen-associated molecular patterns or other …
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
S Lipinski, A Till, C Sina, A Arlt… - Journal of cell …, 2009 - journals.biologists.com
Generation of microbicidal reactive oxygen species (ROS) is a pivotal protective component
of the innate immune system in many eukaryotes. NOD (nucleotide oligomerisation domain …
of the innate immune system in many eukaryotes. NOD (nucleotide oligomerisation domain …
[PDF][PDF] Lipoxin A4 attenuates obesity-induced adipose inflammation and associated liver and kidney disease
The role of inflammation in obesity-related pathologies is well established. We investigated
the therapeutic potential of LipoxinA 4 (LXA 4: 5 (S), 6 (R), 15 (S)-trihydroxy-7E, 9E, 11Z …
the therapeutic potential of LipoxinA 4 (LXA 4: 5 (S), 6 (R), 15 (S)-trihydroxy-7E, 9E, 11Z …
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
D Ellinghaus, H Zhang, S Zeissig, S Lipinski, A Till… - Gastroenterology, 2013 - Elsevier
Background & Aims Genome-wide association studies (GWAS) have identified 140 Crohn's
disease (CD) susceptibility loci. For most loci, the variants that cause disease are not known …
disease (CD) susceptibility loci. For most loci, the variants that cause disease are not known …
Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion
P Rosenstiel, C Sina, C End, M Renner… - The Journal of …, 2007 - journals.aai.org
Mucosal epithelial cell layers are constantly exposed to a complex resident microflora.
Deleted in malignant brain tumors 1 (DMBT1) belongs to the group of secreted scavenger …
Deleted in malignant brain tumors 1 (DMBT1) belongs to the group of secreted scavenger …