Multiple studies suggested using different miRNAs as biomarkers for prognosis of
hepatocellular carcinoma (HCC). We aimed to assemble a miRNA expression database …

There is growing consensus that multigene prognostic tests provide useful complementary
information to tumor size and grade in estrogen receptor (ER)-positive breast cancers. The …

While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …

Background Survival analysis is a cornerstone of medical research, enabling the
assessment of clinical outcomes for disease progression and treatment efficiency. Despite …

In the last decade, optimized treatment for non-small cell lung cancer had lead to improved
prognosis, but the overall survival is still very short. To further understand the molecular …

Cancer hallmark genes are responsible for the most essential phenotypic characteristics of
malignant transformation and progression. In this study, our aim was to estimate the …

Introduction Extensive research is directed to uncover new biomarkers capable to stratify
breast cancer patients into clinically relevant cohorts. However, the overall performance …

Gene or protein expression data are usually represented by metric or at least ordinal
variables. In order to translate a continuous variable into a clinical decision, it is necessary to …

Results The entire database incorporates 1,065 gastric carcinoma samples, gene
expression data. Out of 29 established markers, higher expression of BECN1 (HR= 0.68, p …

The validation of prognostic biomarkers in large independent patient cohorts is a major
bottleneck in ovarian cancer research. We implemented an online tool to assess the …