Faecal microbiota transplantation halts progression of human new-onset type 1 diabetes in a randomised controlled trial

P De Groot, T Nikolic, S Pellegrini, V Sordi… - Gut, 2021 - gut.bmj.com
Objective Type 1 diabetes (T1D) is characterised by islet autoimmunity and beta cell
destruction. A gut microbiota–immunological interplay is involved in the pathophysiology of …

[HTML][HTML] Imaging fetal anatomy

Y Dawood, MFJ Buijtendijk, H Shah, JA Smit… - Seminars in cell & …, 2022 - Elsevier
Due to advancements in ultrasound techniques, the focus of antenatal ultrasound screening
is moving towards the first trimester of pregnancy. The early first trimester however remains …

An interactive three-dimensional digital atlas and quantitative database of human development

BS de Bakker, KH de Jong, J Hagoort, K de Bree… - Science, 2016 - science.org
INTRODUCTION The basic human body plan, the arrangement of organs in the body, is laid
down during embryonic development. Insight into the formation of this plan informs …

[HTML][HTML] The tubarial salivary glands: A potential new organ at risk for radiotherapy

MH Valstar, BS de Bakker, RJHM Steenbakkers… - Radiotherapy and …, 2021 - Elsevier
Introduction The presence of previously unnoticed bilateral macroscopic salivary gland
locations in the human nasopharynx was suspected after visualization by positron emission …

Impact of surgery and anesthesia during early brain development: a perfect storm

K Keunen, NH Sperna Weiland… - Pediatric …, 2022 - Wiley Online Library
Neonatal surgery and concomitant anesthesia coincide with a timeframe of rapid brain
development. The speed and complexity of early brain development superimposed on …

[HTML][HTML] Discrepancies in Embryonic Staging: Towards a Gold Standard

S Flierman, M Tijsterman, M Rousian, BS de Bakker - Life, 2023 - mdpi.com
For over half a century, the Carnegie staging system has been used for the unification of
chronology in human embryo development. Despite the system's establishment as a …

The developmental impacts of natural selection on human pelvic morphology

M Young, D Richard, M Grabowski, BM Auerbach… - Science …, 2022 - science.org
Evolutionary responses to selection for bipedalism and childbirth have shaped the human
pelvis, a structure that differs substantially from that in apes. Morphology related to these …

[HTML][HTML] The development of the human notochord

K de Bree, BS de Bakker, RJ Oostra - PLoS One, 2018 - journals.plos.org
The notochord is a major regulator of embryonic patterning in vertebrates and abnormal
notochordal development is associated with a variety of birth defects in man. Proper …

The development of the human hyoid–larynx complex revisited

BS de Bakker, HM de Bakker… - The …, 2018 - Wiley Online Library
Objectives/Hypothesis The hyoid–larynx complex is highly prone to anatomical variation.
The etiology of anatomical variants such as Eagle's syndrome and the aberrant hyoid …

Towards a 3-dimensional atlas of the developing human embryo: the Amsterdam experience

BS de Bakker, KH de Jong, J Hagoort, RJ Oostra… - Reproductive …, 2012 - Elsevier
Knowledge of complex morphogenetic processes that occur during embryonic development
is essential for understanding anatomy and to get insight in the pathogenesis of congenital …