Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis
W Huang, DM Booth, MC Cane, M Chvanov, MA Javed… - Gut, 2014 - gut.bmj.com
Objective Non-oxidative metabolism of ethanol (NOME) produces fatty acid ethyl esters
(FAEEs) via carboxylester lipase (CEL) and other enzyme action implicated in mitochondrial …
(FAEEs) via carboxylester lipase (CEL) and other enzyme action implicated in mitochondrial …
Trichloroethene-induced autoimmune response in female MRL+/+ mice
MF Khan, BS Kaphalia, BS Prabhakar, MF Kanz… - Toxicology and applied …, 1995 - Elsevier
Trichloroethene (TCE) has been implicated in the pathogenesis of autoimmune diseases
such as systemic lupus erythematosus (SLE) and scleroderma in humans. However …
such as systemic lupus erythematosus (SLE) and scleroderma in humans. However …
[HTML][HTML] Recent advances in understanding the complexity of alcohol-induced pancreatic dysfunction and pancreatitis development
K Rasineni, MP Srinivasan, AN Balamurugan… - Biomolecules, 2020 - mdpi.com
Chronic excessive alcohol use is a well-recognized risk factor for pancreatic dysfunction and
pancreatitis development. Evidence from in vivo and in vitro studies indicates that the …
pancreatitis development. Evidence from in vivo and in vitro studies indicates that the …
Lipidomic changes in rat liver after long-term exposure to ethanol
H Fernando, KK Bhopale, S Kondraganti… - Toxicology and applied …, 2011 - Elsevier
Alcoholic liver disease (ALD) is a serious health problem with significant morbidity and
mortality. In this study we examined the progression of ALD along with lipidomic changes in …
mortality. In this study we examined the progression of ALD along with lipidomic changes in …
Fatty acid ethyl esters: markers of alcohol abuse and alcoholism
BS Kaphalia, P Cai, MF Khan, AO Okorodudu… - Alcohol, 2004 - Elsevier
Chronic alcoholism, which is associated with hepatic, pancreatic, and myocardial diseases,
is one of the major health problems in the United States with high morbidity and mortality …
is one of the major health problems in the United States with high morbidity and mortality …
Organochlorine pesticide residues in different Indian cereals, pulses, spices, vegetables, fruits, milk, butter, deshi ghee, and edible oils
BS Kaphalia, R Takroo, S Mehrotra… - Journal of the …, 1990 - academic.oup.com
A total of 244 samples of cereals (wheat flour, rice, and maize), pulses (arhar, moong, gram,
lentil, and black gram), spices (turmeric, chili, coriander, and black pepper), vegetables …
lentil, and black gram), spices (turmeric, chili, coriander, and black pepper), vegetables …
Chronic exposure to trichloroethene causes early onset of SLE-like disease in female MRL+/+ mice
P Cai, R König, PJ Boor, S Kondraganti… - Toxicology and applied …, 2008 - Elsevier
Trichloroethene (TCE) exacerbates the development of autoimmune responses in
autoimmune-prone MRL+/+ mice. Although TCE-mediated autoimmune responses are …
autoimmune-prone MRL+/+ mice. Although TCE-mediated autoimmune responses are …
1H and 31P NMR Lipidome of Ethanol‐Induced Fatty Liver
H Fernando, S Kondraganti, KK Bhopale… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: Hepatic steatosis (fatty liver), an early and reversible stage of alcoholic liver
disease, is characterized by triglyceride deposition in hepatocytes, which can advance to …
disease, is characterized by triglyceride deposition in hepatocytes, which can advance to …
Efficient high performance liquid chromatograph/ultraviolet method for determination of diclofenac and 4′-hydroxydiclofenac in rat serum
L Kaphalia, BS Kaphalia, S Kumar, MF Kanz… - … of Chromatography B, 2006 - Elsevier
A rapid and sensitive high-performance liquid chromatographic method was developed for
determination of diclofenac and its major metabolite, 4′-hydroxydiclofenac, in serum from …
determination of diclofenac and its major metabolite, 4′-hydroxydiclofenac, in serum from …
Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: role of nonoxidative metabolism
H Wu, P Cai, DL Clemens, TR Jerrells… - Toxicology and applied …, 2006 - Elsevier
Chronic alcohol abuse, a major health problem, causes liver and pancreatic diseases and is
known to impair hepatic alcohol dehydrogenase (ADH). Hepatic ADH-catalyzed oxidation of …
known to impair hepatic alcohol dehydrogenase (ADH). Hepatic ADH-catalyzed oxidation of …