Molecular viral oncology of hepatocellular carcinoma

TM Block, AS Mehta, CJ Fimmel, R Jordan - Oncogene, 2003 - nature.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer, but the third leading
cause of cancer death, in the world, with more than 500 000 fatalities annually. The major …

GP73, a resident Golgi glycoprotein, is a novel serum marker for hepatocellular carcinoma

JA Marrero, PR Romano, O Nikolaeva, L Steel… - Journal of …, 2005 - Elsevier
BACKGROUND/AIMS: Golgi protein-73 (GP73) is up-regulated in hepatocellular carcinoma
(HCC). The aims of this study were to determine if GP73 is detected in the serum, and to …

A concise review of serum markers for hepatocellular cancer

LM Wright, JT Kreikemeier, CJ Fimmel - Cancer Detection and Prevention, 2007 - Elsevier
Background: The rising incidence of hepatocellular cancer in the US and worldwide has
sparked a renewed interest in HCC serum markers. HCC typically develops in patients with …

GP73, a novel Golgi-localized protein upregulated by viral infection

RD Kladney, GA Bulla, L Guo, AL Mason, AE Tollefson… - Gene, 2000 - Elsevier
We report the isolation and characterization of GP73, a novel 73kDa human Golgi protein.
The GP73 cDNA was cloned by differential screening of a cDNA library derived from the liver …

Expression of GP73, a resident Golgi membrane protein, in viral and nonviral liver disease

RD Kladney, X Cui, GA Bulla, EM Brunt, CJ Fimmel - Hepatology, 2002 - Elsevier
GP73 is a novel type II Golgi membrane protein of unknown function that is expressed in the
hepatocytes of patients with adult giant-cell hepatitis (Gene 2000; 249: 53-65). Its expression …

Disease-and cell-specific expression of GP73 in human liver disease

R Iftikhar, RD Kladney, N Havlioglu… - Official journal of the …, 2004 - journals.lww.com
OBJECTIVES GP73, a Golgi membrane protein, is expressed at high levels in hepatocytes
of patients with decompensated cirrhosis. Its expression in other forms of liver disease has …

Management of incidental liver lesions on CT: a white paper of the ACR Incidental Findings Committee

RM Gore, PJ Pickhardt, KJ Mortele, EK Fishman… - Journal of the American …, 2017 - Elsevier
Abstract The ACR Committee on Incidental Findings presents recommendations for
managing liver lesions that are incidentally detected on CT. These recommendations …

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer

S Varambally, B Laxman, R Mehra, Q Cao… - Neoplasia, 2008 - Elsevier
Prostate cancer is the most common type of tumor found in American men and is the second
leading cause of cancer death in males. To identify biomarkers that distinguish prostate …

Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption

S Puri, C Bachert, CJ Fimmel, AD Linstedt - Traffic, 2002 - Wiley Online Library
The cis‐Golgi protein GPP130 reversibly redistributes to endosomes upon pH disruption, but
the identity of the endosomes and the involved cycling route are unknown. It is also …

Long-term ambulatory gastric pH monitoring: validation of a new method and effect of H2-antagonists

CJ Fimmel, A Etienne, T Cilluffo, C Ritter, T Gasser… - Gastroenterology, 1985 - Elsevier
A new ambulatory monitoring system was evaluated for long-term measurements of gastric
acidity. A close correlation was observed between values indicated by the pH electrode of …