Citrulline increases arginine pools and restores nitrogen balance after massive intestinal resection

S Osowska, C Moinard, C Loï, N Neveux, L Cynober - Gut, 2004 - gut.bmj.com
Objective: Arginine supplementation seems logical in situations where this amino acid
becomes essential, for example after massive intestinal resection. Arginine is taken up and …

Glutamate: a safe nutrient, not just a simple additive

C Loï, L Cynober - Annals of Nutrition and Metabolism, 2022 - karger.com
Abstract Background: In 2017, a European Food Safety Authority (EFSA) opinion on the use
of glutamate and its salts as food additives led to an Acceptable Daily Intake (ADI) of 30 …

Citrulline protects human retinal pigment epithelium from hydrogen peroxide and iron/ascorbate induced damages

…, N Jacquemot, C Blavignac, C Loï… - Journal of Cellular …, 2022 - Wiley Online Library
Oxidative stress plays an important role in the ageing of the retina and in the pathogenesis
of retinal diseases such as age‐related macular degeneration (ARMD). Hydrogen peroxide …

Increasing plasma glutamine in postoperative patients fed an arginine-rich immune-enhancing diet—A pharmacokinetic randomized controlled study

C Loï, JF Zazzo, E Delpierre, C Niddam… - Critical care …, 2009 - journals.lww.com
Objective: Immune-enhancing diets (IEDs) rich in arginine (ARG) reduce morbi-mortality in
trauma and surgical patients. Among the pharmaconutrients inducing these effects, ARG …

[HTML][HTML] Incorporation and metabolism of dietary trans isomers of linolenic acid alter the fatty acid profile of rat tissues

C Loï, JM Chardigny, S Almanza, L Leclere… - The Journal of …, 2000 - Elsevier
To study the influence on lipid metabolism and platelet aggregation of the fatty acid
isomerization that occurs during heat treatment, weanling rats were fed for 8 wk a diet …

Ornithine α-ketoglutarate metabolism in the healthy rat in the postabsorptive state

C Loï, S Nakib, N Neveux, F Arnaud-Battandier… - Metabolism, 2005 - Elsevier
To gain further insight into the ability of ornithine α-ketoglutarate (OKG) to generate key
metabolites, the aim of this work was to study the short-term metabolism, that is, 1 hour after …

Simultaneous determination of retinol and α-tocopherol in polymeric diets for enteral nutrition

…, S Nakib, JP De Bandt, L Cynober, C Loï - … of Chromatography A, 2008 - Elsevier
Existing methods for simultaneous measurements of retinol and α-tocopherol in enteral
formulas require large sample and solvent volumes and are time-consuming and costly. We …

Effects of three trans isomers of eicosapentaenoic acid on rat platelet aggregation and arachidonic acid metabolism

C Loï, JM Chardigny, O Berdeaux… - Thrombosis and …, 1998 - thieme-connect.com
Three trans isomers of eicosapentaenoic acid (EPA) were added to rat platelets stimulated
with arachidonic acid (AA) in order to compare their effects on platelet aggregation and on …

An oligomeric diet limits the response to injury in traumatic brain-injured rats

C Moinard, E Delpierre, C Loï, N Neveux… - Journal of …, 2013 - liebertpub.com
Adequate nutritional support is a major challenge in brain injury patients, because
malnutrition cannot be reversed by standard enteral nutrition. We hypothesized that an …

Does the ornithine–α-ketoglutarate ratio influence ornithine α-ketoglutarate metabolism in healthy rats?

C Loï, D Hamani, C Moinard, L Bishoff, N Neveux… - Metabolism, 2007 - Elsevier
Ornithine α-ketoglutarate (OKG) is a salt composed of 2 molecules of ornithine (ORN) and
one molecule of α-ketoglutarate (αKG). OKG has been used successfully via oral, enteral …