User profiles for "author:Carlo Federico Perno"

Carlo Federico Perno

Università di Milano
Verified email at uniroma2.it
Cited by 25787

European guidelines on the clinical management of HIV-1 tropism testing

LPR Vandekerckhove, AMJ Wensing… - The Lancet infectious …, 2011 - thelancet.com
Viral tropism is the ability of viruses to enter and infect specific host cells and is based on the
ability of viruses to bind to receptors on those cells. Testing for HIV tropism is recommended …

[HTML][HTML] HIV-1 genetic variability and clinical implications

MM Santoro, CF Perno - International Scholarly Research Notices, 2013 - hindawi.com
Despite advances in antiretroviral therapy that have revolutionized HIV disease
management, effective control of the HIV infection pandemic remains elusive. Beyond the …

Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir

S Aquaro, R Caliò, J Balzarini, MC Bellocchi, E Garaci… - Antiviral research, 2002 - Elsevier
Cells of macrophage lineage represent a key target of human immunodeficiency virus (HIV)
in addition to CD4-lymphocytes. The absolute number of infected macrophages in the body …

1, 2, 3-Triazole-[2, 5-Bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole 2'', 2''-dioxide)(TSAO) Analogs: Synthesis and Anti-HIV …

R Alvarez, S Velazquez, A San-Felix… - Journal of medicinal …, 1994 - ACS Publications
Several 4-or 5-monosubsituted and 4, 5-disubstituted 1, 2, 3-triazole analogues of the anti-
HIV-1 lead compound [l-[2,, 5,-bis-0-(ieri-butyldimethylsilyl)-/?-D-ribofuranosyl] thymine]-3' …

[PDF][PDF] Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections

S Terreri, EP Mortari, MR Vinci, C Russo, C Alteri… - Cell host & …, 2022 - cell.com
Breakthrough SARS-CoV-2 infections in fully vaccinated individuals are considered a
consequence of waning immunity. Serum antibodies represent the most measurable …

Safety and efficacy of anti-il6-receptor tocilizumab use in severe and critical patients affected by coronavirus disease 2019: A comparative analysis

R Rossotti, G Travi, N Ughi, M Corradin, C Baiguera… - Journal of Infection, 2020 - Elsevier
Background As the novel SARS-CoV-2 pandemic occurred, no specific treatment was yet
available. Inflammatory response secondary to viral infection might be the driver of severe …

In vivo activity against HIV and favorable toxicity profile of 2′, 3′-dideoxyinosine

R Yarchoan, H Mitsuya, RV Thomas, JM Pluda… - Science, 1989 - science.org
The purine analog 2′, 3′-dideoxyinosine (ddI), which has anti-retroviral activity in vitro
was administered for up to 42 weeks to 26 patients with acquired immunodeficiency …

[HTML][HTML] Humoral and cellular response following vaccination with the BNT162b2 mRNA COVID-19 vaccine in patients affected by primary immunodeficiencies

D Amodio, A Ruggiero, M Sgrulletti, C Pighi… - Frontiers in …, 2021 - frontiersin.org
Mass SARS-Cov-2 vaccination campaign represents the only strategy to defeat the global
pandemic we are facing. Immunocompromised patients represent a vulnerable population at …

[HTML][HTML] Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients

C Alteri, V Cento, M Antonello, L Colagrossi, M Merli… - PloS one, 2020 - journals.plos.org
Since SARS-CoV-2-based disease (COVID-19) spreads as a pandemic, the necessity of a
highly sensitive molecular diagnosis that can drastically reduce false negatives reverse …

[HTML][HTML] Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy

C Alteri, V Cento, A Piralla, V Costabile… - Nature …, 2021 - nature.com
Abstract From February to April 2020, Lombardy (Italy) reported the highest numbers of
SARS-CoV-2 cases worldwide. By analyzing 346 whole SARS-CoV-2 genomes, we …