The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta‐analysis, and clinical practice guideline: a systematic …
X Zeng, Y Zhang, JSW Kwong, C Zhang… - Journal of evidence …, 2015 - Wiley Online Library
Objective To systematically review the methodological assessment tools for pre‐clinical and
clinical studies, systematic review and meta‐analysis, and clinical practice guideline …
clinical studies, systematic review and meta‐analysis, and clinical practice guideline …
Lanthanide nanoparticles: from design toward bioimaging and therapy
Lanthanides refer to the 15 elements located at the sixth period and IIIB group in the periodic
table, ranging from lanthanum to lutetium, with the electronic configuration of [Xe] 4f n–1 5d …
table, ranging from lanthanum to lutetium, with the electronic configuration of [Xe] 4f n–1 5d …
Vemurafenib: the first drug approved for BRAF-mutant cancer
G Bollag, J Tsai, J Zhang, C Zhang, P Ibrahim… - Nature reviews Drug …, 2012 - nature.com
The identification of driver oncogenes has provided important targets for drugs that can
change the landscape of cancer therapies. One such example is the BRAF oncogene, which …
change the landscape of cancer therapies. One such example is the BRAF oncogene, which …
[HTML][HTML] Pathological findings of COVID-19 associated with acute respiratory distress syndrome
Z Xu, L Shi, Y Wang, J Zhang, L Huang… - The Lancet respiratory …, 2020 - thelancet.com
which has subsequently affected 26 countries worldwide. In general, COVID-19 is an acute
resolved disease but it can also be deadly, with a 2% case fatality rate. Severe disease …
resolved disease but it can also be deadly, with a 2% case fatality rate. Severe disease …
[HTML][HTML] Liver injury in COVID-19: management and challenges
C Zhang, L Shi, FS Wang - The lancet Gastroenterology & …, 2020 - thelancet.com
In December, 2019, an outbreak of a novel coronavirus (severe acute respiratory syndrome
coronavirus 2 [SARS-CoV-2], previously 2019-nCoV) started in Wuhan, China, and has …
coronavirus 2 [SARS-CoV-2], previously 2019-nCoV) started in Wuhan, China, and has …
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
G Bollag, P Hirth, J Tsai, J Zhang, PN Ibrahim, H Cho… - Nature, 2010 - nature.com
B-RAF is the most frequently mutated protein kinase in human cancers. The finding that
oncogenic mutations in BRAF are common in melanoma, followed by the demonstration that …
oncogenic mutations in BRAF are common in melanoma, followed by the demonstration that …
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
Tumours with mutant BRAF are dependent on the RAF–MEK–ERK signalling pathway for
their growth,,. We found that ATP-competitive RAF inhibitors inhibit ERK signalling in cells …
their growth,,. We found that ATP-competitive RAF inhibitors inhibit ERK signalling in cells …
A compact X-ray free-electron laser emitting in the sub-ångström region
T Ishikawa, H Aoyagi, T Asaka, Y Asano, N Azumi… - nature …, 2012 - nature.com
The free-electron laser, first proposed by Madey in 1971, has significantly reduced laser
wavelengths to the vacuum ultraviolet, and soft X-ray regions. Recently, an X-ray free …
wavelengths to the vacuum ultraviolet, and soft X-ray regions. Recently, an X-ray free …
T-gcn: A temporal graph convolutional network for traffic prediction
Accurate and real-time traffic forecasting plays an important role in the intelligent traffic
system and is of great significance for urban traffic planning, traffic management, and traffic …
system and is of great significance for urban traffic planning, traffic management, and traffic …
[HTML][HTML] Trial of endovascular treatment of acute basilar-artery occlusion
C Tao, RG Nogueira, Y Zhu, J Sun, H Han… - … England Journal of …, 2022 - Mass Medical Soc
Background Data from trials investigating the effects and risks of endovascular
thrombectomy for the treatment of stroke due to basilar-artery occlusion are limited. Methods …
thrombectomy for the treatment of stroke due to basilar-artery occlusion are limited. Methods …