Advances and perspectives in in vitro human gut fermentation modeling

AN Payne, A Zihler, C Chassard, C Lacroix - Trends in biotechnology, 2012 - cell.com
The gut microbiota is a highly specialized organ containing host-specific assemblages of
microbes whereby metabolic activity directly impacts human health and disease. In vitro gut …

Impact of human milk bacteria and oligosaccharides on neonatal gut microbiota establishment and gut health

T Jost, C Lacroix, C Braegger, C Chassard - Nutrition reviews, 2015 - academic.oup.com
Neonatal gut microbiota establishment represents a crucial stage for gut maturation,
metabolic and immunologic programming, and consequently short-and long-term health …

Gut microbial adaptation to dietary consumption of fructose, artificial sweeteners and sugar alcohols: implications for host–microbe interactions contributing to obesity

AN Payne, C Chassard, C Lacroix - Obesity reviews, 2012 - Wiley Online Library
The Western diet, comprised of highly refined carbohydrates and fat but reduced complex
plant polysaccharides, has been attributed to the prevalence of obesity. A concomitant rise …

Iron fortification adversely affects the gut microbiome, increases pathogen abundance and induces intestinal inflammation in Kenyan infants

T Jaeggi, GAM Kortman, D Moretti, C Chassard… - Gut, 2015 - gut.bmj.com
Background In-home iron fortification for infants in developing countries is recommended for
control of anaemia, but low absorption typically results in> 80% of the iron passing into the …

Vertical mother–neonate transfer of maternal gut bacteria via breastfeeding

T Jost, C Lacroix, CP Braegger… - Environmental …, 2014 - Wiley Online Library
Breast milk has recently been recognized as source of commensal and potential probiotic
bacteria. The present study investigated whether viable strains of gut‐associated obligate …

[HTML][HTML] The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire

MB Zimmermann, C Chassard, F Rohner… - The American journal of …, 2010 - Elsevier
Background: Iron is essential for the growth and virulence of many pathogenic
enterobacteria, whereas beneficial barrier bacteria, such as lactobacilli, do not require iron …

Functional dysbiosis within the gut microbiota of patients with constipated‐irritable bowel syndrome

C Chassard, M Dapoigny, KP Scott… - Alimentary …, 2012 - Wiley Online Library
Background The role of the gut microbiota in patho‐physiology of irritable bowel syndrome
(IBS) is suggested by several studies. However, standard cultural and molecular methods …

High levels of butyrate and propionate in early life are associated with protection against atopy

C Roduit, R Frei, R Ferstl, S Loeliger, P Westermann… - Allergy, 2019 - Wiley Online Library
Background Dietary changes are suggested to play a role in the increasing prevalence of
allergic diseases and asthma. Short‐chain fatty acids (SCFA s) are metabolites present in …

Assessment of bacterial diversity in breast milk using culture-dependent and culture-independent approaches

T Jost, C Lacroix, C Braegger… - British Journal of Nutrition, 2013 - cambridge.org
Initial neonatal gut colonisation is a crucial stage for developing a healthy physiology,
beneficially influenced by breast-feeding. Breast milk has been shown not only to provide …

[HTML][HTML] New insights in gut microbiota establishment in healthy breast fed neonates

T Jost, C Lacroix, CP Braegger, C Chassard - 2012 - journals.plos.org
The establishment of a pioneer gut microbiota is increasingly recognized as a crucial stage
in neonatal development influencing health throughout life. While current knowledge is …