Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease

G Targher, CP Day, E Bonora - New England Journal of Medicine, 2010 - Mass Medical Soc
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease | NEJM
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Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

QM Anstee, G Targher, CP Day - Nature reviews Gastroenterology & …, 2013 - nature.com
NAFLD is a spectrum of progressive liver disease that encompasses simple steatosis,
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …

Nonalcoholic fatty liver disease

EM Brunt, VWS Wong, V Nobili, CP Day… - Nature reviews Disease …, 2015 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a disorder characterized by excess accumulation
of fat in hepatocytes (nonalcoholic fatty liver (NAFL)); in up to 40% of individuals, there are …

[PDF][PDF] The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD

P Angulo, JM Hui, G Marchesini, E Bugianesi… - …, 2007 - Wiley Online Library
Patients with nonalcoholic fatty liver disease (NAFLD) and advanced liver fibrosis are at the
highest risk for progressing to end‐stage liver disease. We constructed and validated a …

Steatohepatitis: a tale of two “hits”?

CP Day, OFW James - Gastroenterology, 1998 - Elsevier
Steatohepatitis: A tale of two “hits”? - ScienceDirect Skip to main contentSkip to article
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Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

GP Aithal, CP Day, PJL Kesteven, AK Daly - The Lancet, 1999 - thelancet.com
Summary Background The cytochrome P450 CYP2C9 is responsible for the metabolism of S-
warfarin. Two known allelic variants CYP2C9* 2 and CYP2C9* 3 differ from the wild type …

QT dispersion: an indication of arrhythmia risk in patients with long QT intervals.

CP Day, JM McComb, RW Campbell - Heart, 1990 - heart.bmj.com
Homogeneity of recovery time protects against arrhythmias whereas dispersion of recovery
time is arrhythmogenic. A single surface electrocardiographic QT interval gives no …

[HTML][HTML] Modeling nafld disease burden in china, france, germany, italy, japan, spain, united kingdom, and united states for the period 2016–2030

C Estes, QM Anstee, MT Arias-Loste, H Bantel… - Journal of …, 2018 - Elsevier
Background & Aims Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic
steatohepatitis (NASH) are increasingly a cause of cirrhosis and hepatocellular carcinoma …

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

AK Daly, PT Donaldson, P Bhatnagar, Y Shen, I Pe'er… - Nature …, 2009 - nature.com
Drug-induced liver injury (DILI) is an important cause of serious liver disease. The
antimicrobial agent flucloxacillin is a common cause of DILI, but the genetic basis for …

[PDF][PDF] Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European Liver Fibrosis Panel and exploring simple markers

IN Guha, J Parkes, P Roderick, D Chattopadhyay… - …, 2008 - Wiley Online Library
The detection of fibrosis within nonalcoholic fatty liver disease (NAFLD) is important for
ascertaining prognosis and the stratification of patients for emerging therapeutic …