Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome

M Henström, L Diekmann, F Bonfiglio, F Hadizadeh… - Gut, 2018 - gut.bmj.com
Objective IBS is a common gut disorder of uncertain pathogenesis. Among other factors,
genetics and certain foods are proposed to contribute. Congenital sucrase–isomaltase …

Genome-wide search for markers associated with osteochondrosis in Hanoverian warmblood horses

C Dierks, K Löhring, V Lampe, C Wittwer… - Mammalian …, 2007 - Springer
A genome-wide scan was performed to detect quantitative trait loci (QTLs) for
osteochondrosis (OC) and osteochondrosis dissecans (OCD) in horses. The marker set …

[HTML][HTML] Two-Exon Skipping within MLPH Is Associated with Coat Color Dilution in Rabbits

S Lehner, M Gähle, C Dierks, R Stelter, J Gerber… - PLoS …, 2013 - journals.plos.org
Coat color dilution turns black coat color to blue and red color to cream and is a
characteristic in many mammalian species. Matings among Netherland Dwarf, Loh, and …

[HTML][HTML] Cultivation and characterization of primordial germ cells from blue layer hybrids (Araucana crossbreeds) and generation of germline chimeric chickens

S Altgilbers, S Klein, C Dierks, S Weigend, WA Kues - Scientific Reports, 2021 - nature.com
The chicken (Gallus gallus) is one of the most common and widespread domestic species,
with an estimated total population of 25 billion birds worldwide. The vast majority of chickens …

[HTML][HTML] Genome-Wide Association Study Identifies Phospholipase C zeta 1 (PLCz1) as a Stallion Fertility Locus in Hanoverian Warmblood Horses

R Schrimpf, C Dierks, G Martinsson, H Sieme, O Distl - PLoS One, 2014 - journals.plos.org
A consistently high level of stallion fertility plays an economically important role in modern
horse breeding. We performed a genome-wide association study for estimated breeding …

[HTML][HTML] A Single Nucleotide Polymorphism within the Interferon Gamma Receptor 2 Gene Perfectly Coincides with Polledness in Holstein Cattle

S Glatzer, NJ Merten, C Dierks, A Wöhlke, U Philipp… - PloS one, 2013 - journals.plos.org
Polledness is a high impact trait in modern milk and beef production to meet the demands of
animal welfare and work safety. Previous studies have mapped the polled-locus to the …

Associations between candidate gene markers at a quantitative trait locus on equine chromosome 4 responsible for osteochondrosis dissecans in fetlock joints of …

C Wittwer, C Dierks, H Hamann, O Distl - Journal of Heredity, 2008 - academic.oup.com
A previously accomplished whole-genome scan for osteochondrosis (OC) and OC
dissecans (OCD) in South German Coldblood horses using 250 microsatellite markers …

Identification of a new quantitative trait locus on equine chromosome 18 responsible for osteochondrosis in Hanoverian warmblood horses

V Lampe, C Dierks, K Komm, O Distl - Journal of animal science, 2009 - academic.oup.com
In this study we present a newly detected QTL associated with osteochondrosis in
Hanoverian warmblood horses on equine chromosome 18 (ECA18). We developed a highly …

Refinement of a quantitative trait locus on equine chromosome 5 responsible for fetlock osteochondrosis in Hanoverian warmblood horses

V Lampe, C Dierks, O Distl - Animal genetics, 2009 - Wiley Online Library
In this report, we provide 29 new informative microsatellites distributed over a region of 21
Mb on horse chromosome (ECA) 5 and refine a quantitative trait locus (QTL) for fetlock …

[HTML][HTML] Quantitative analysis of CRISPR/Cas9-mediated provirus deletion in blue egg layer chicken PGCs by digital PCR

S Altgilbers, C Dierks, S Klein, S Weigend, WA Kues - Scientific Reports, 2022 - nature.com
Primordial germ cells (PGCs), the precursors of sperm and oocytes, pass on the genetic
material to the next generation. The previously established culture system of chicken PGCs …