Systemic and local inflammatory processes have a key, mainly detrimental role in the
pathophysiology of ischemic stroke. Currently, little is known about endogenous …

Summary Interleukin (IL)-10-deficient (IL-10−/−) mice develop colitis under specific
pathogen-free (SPF) conditions and remain disease free if kept sterile (germ free [GF]). We …

Experimental data suggest the antimicrobial peptide hepcidin as a central regulator in iron
homeostasis. In this study, we characterized the expression of human hepcidin in …

Interleukin-2 (IL-2) amplifies immune stimuli and influences B cell differentiation. IL-2-
deficient mice spontaneously develop intestinal inflammation if raised under specific …

Background & Aims: Normal resident bacteria are required for development of colitis in
several rodent models. We determined whether bacterial stimulation is necessary for both …

Background and aims Inappropriate immune responses contribute to the continuous
stimulation of the intestinal immune system in chronic inflammatory bowel disease (IBD) …

Ultrasmall gold nanoparticles (2 nm) easily penetrate the membranes of intestinal murine
epithelial cells (MODE‐K) and colorectal cancer cells (CT‐26). They are also taken up by 3D …

BACKGROUND AND PURPOSE: The timing and mechanisms of protection by hyperbaric
oxygen (HBO) in cerebral ischemia have only been partially elucidated. We monitored the …

Background and Purpose: Chronic inflammatory bowel diseases (IBD) frequently affect
extraintestinal organs including the liver. Since limited evidence suggests the presence of …

Hyperbaric oxygen (HBO) has been shown to preserve the integrity of the blood–brain
barrier after cerebral ischemia. However, the underlying molecular mechanisms are …