Colorectal cancer (CRC) presents a considerable disease burden worldwide. The human
colon is also an anatomical location with the largest number of microbes. It is natural …

Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

Bacteria that colonize the intestine, invade intestinal epithelial cells, and/or produce one or
more toxins are important etiologies of diarrheal disease in both industrialized and …

The intestinal flora may promote colon tumor formation. Here we explore immunologic
mechanisms of colonic carcinogenesis by a human colonic bacterium, enterotoxigenic …

We examined the immune microenvironment of primary colorectal cancer using
immunohistochemistry, laser capture microdissection/qRT-PCR, flow cytometry, and …

Most patients diagnosed with resected pancreatic adenocarcinoma (PDAC) survive less
than 5 years, but a minor subset survives longer. Here, we dissect the role of the tumor …

Individuals with sporadic colorectal cancer (CRC) frequently harbor abnormalities in the
composition of the gut microbiome; however, the microbiota associated with precancerous …

Environmental factors clearly affect colorectal cancer (CRC) incidence, but the mechanisms
through which these factors function are unknown. One prime candidate is an altered …

It is estimated that the etiology of 20–30% of epithelial cancers is directly associated with
inflammation, although the direct molecular events linking inflammation and carcinogenesis …

A dynamic partnership: Celebrating our gut flora - ScienceDirect Skip to main contentSkip to
article Elsevier logo Journals & Books Search RegisterSign in View PDF Download full …