The diagnosis of acute appendicitis is predominantly a clinical one; many patients present
with a typical history and examination findings. The cause of acute appendicitis is unknown …

Background Antibiotic treatment has been shown to be effective in treating selected patients
with acute appendicitis, and three randomized controlled trials (RCTs) have compared the …

Abstract Background Coronavirus disease (COVID-19) has caused global disruption to
health care. Non-urgent elective surgical cases have been cancelled, outpatient clinics have …

Background Anxiety, depression and nongastrointestinal symptoms are often prominent in
irritable bowel syndrome (IBS), but their relative value in patient management has not been …

Background This randomized controlled trial compared the cost–utility of early laparoscopic
cholecystectomy with that for conventional management of newly diagnosed acute …

Background Recurrent abdominal pain is reported by a third of patients with diverticulosis,
particularly those with previous episodes of acute diverticulitis. The current understanding of …

Objectives. We obtained contextual information regarding documented barriers to HIV
clinical trial participation among Black men who have sex with men (MSM), and explored …

Objective To determine the risk of diverticular perforation associated with current and ever
use of corticosteroids, opiate analgesics, non-steroidal anti-inflammatory drugs, aspirin …

Some patients with colonic diverticula suffer recurrent abdominal pain and exhibit visceral
hypersensitivity, though the mechanism is unclear. Prior diverticulitis increases the risk of …

Objective: To determine the absolute and relative risk of acute appendicitis during the
antepartum and postpartum periods compared with the time outside pregnancy among …