Bovine colostrum is a health food supplement which prevents NSAID induced gut damage
RJ Playford, DN Floyd, CE Macdonald, DP Calnan… - Gut, 1999 - gut.bmj.com
BACKGROUND Non-steroidal anti-inflammatory drugs (NSAIDs) are effective for arthritis but
cause gastrointestinal injury. Bovine colostrum is a rich source of growth factors and is …
cause gastrointestinal injury. Bovine colostrum is a rich source of growth factors and is …
Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability
RJ Playford, CE MACDONALD, DP CALNAN… - Clinical …, 2001 - portlandpress.com
Non-steroidal anti-inflammatory drugs (NSAIDs) are effective analgesics but cause
gastrointestinal injury. Present prophylactic measures are suboptimal and novel therapies …
gastrointestinal injury. Present prophylactic measures are suboptimal and novel therapies …
Epidermal growth factor is digested to smaller, less active forms in acidic gastric juice
RJ Playford, T Marchbank, DP Calnan, J Calam… - Gastroenterology, 1995 - Elsevier
Background/Aims: Epidermal growth factor (EGF) is present in gastric juice and has potent
mitogenic properties. The stability of EGF in gastric juice under various physiological and …
mitogenic properties. The stability of EGF in gastric juice under various physiological and …
The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS
DP Calnan, BR Westley, FEB May… - The Journal of …, 1999 - Wiley Online Library
TFF1 is a 60‐amino acid peptide produced in normal gastric mucosa which forms dimers
spontaneously. Tumours of patients with gastric cancer usually have reduced TFF1 levels …
spontaneously. Tumours of patients with gastric cancer usually have reduced TFF1 levels …
Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects
T Marchbank, BR Westley, FEB May… - The Journal of …, 1998 - Wiley Online Library
Human pS2 (trefoil factor family 1, TFF1), a 60‐amino acid member of the trefoil peptide
family, forms dimers via Cys58 and may stimulate gut repair. The effects of dimeric pS2 …
family, forms dimers via Cys58 and may stimulate gut repair. The effects of dimeric pS2 …
Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulum
MG Waugh, S Minogue, JS Anderson… - Biochemical …, 2003 - portlandpress.com
Different phosphoinositides are synthesized in cell membranes in order to perform a variety
of functions. One of the most abundant of these lipids is phosphatidylinositol (PI) 4 …
of functions. One of the most abundant of these lipids is phosphatidylinositol (PI) 4 …
Potency and stability of C terminal truncated human epidermal growth factor
DP Calnan, A Fagbemi, J Berlanga-Acosta… - Gut, 2000 - gut.bmj.com
INTRODUCTION Epidermal growth factor (EGF) is normally present as EGF1–53. A variety
of C terminal truncated forms have been used in preliminary trials for treating gastrointestinal …
of C terminal truncated forms have been used in preliminary trials for treating gastrointestinal …
[HTML][HTML] Gastrointestinal injury and Colostrum
RJ PLAYFORD, CE MACDONALD, DP CALNAN… - colostrumresearch.org
Non-steroidal anti-inflammatory drugs (NSAIDs) are effective analgesics but cause
gastrointestinal injury. Present prophylactic measures are suboptimal and novel therapies …
gastrointestinal injury. Present prophylactic measures are suboptimal and novel therapies …
[CITATION][C] Clinical trial of, bovine colostrum for protection against NSAID-induced enteropathy
CE Macdonald, DP Calnan, T Podas, W Johnson… - Gastroenterology, 1998 - infona.pl
Clinical trial of, bovine colostrum for protection against NSAID-induced enteropathy × Close
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[CITATION][C] Co-administration of the health food supplement, bovine colostrum, reduces the acute NSAID-induced increase in intestinal permeability
RJ Playford, CE Macdonald, DP Calnan, DN Floyd… - Clin Sci, 2001