Background Time to treatment matters in traumatic haemorrhage but the optimal prehospital
use of blood in major trauma remains uncertain. We investigated whether use of packed red …

BACKGROUND Whole blood is optimal for resuscitation of traumatic hemorrhage. Walking
Blood Banks provide fresh whole blood (FWB) where conventional blood components or …

Background Haemorrhage is a major cause of mortality and morbidity following both military
and civilian trauma. Haemostatic dressings may offer effective haemorrhage control as part …

Background The optimal technique for gastrointestinal anastomosis remains controversial in
emergency laparotomy. The aim of this meta-analysis was to compare outcomes of stapled …

Background Almost all studies that have investigated the immune response to trauma have
analysed blood samples acquired post-hospital admission. Thus, we know little of the …

BackgroundThe coronavirus disease 2019 (COVID-19) pandemic is likely to lead to a
significant increase in mental health disorders among healthcare workers (HCW). AimsWe …

Background: Trauma patients are vulnerable to coagulopathy and inflammatory dysfunction
associated with endotheliopathy of trauma (EoT). In vitro evidence has suggested that …

BACKGROUND Endothelial cell damage and glycocalyx shedding after trauma can
increase the risk of inflammation, coagulopathy, vascular permeability, and death. Bedside …

Background Temporary defunctioning ileostomy can reduce the consequences of
anastomotic leak following low anterior resection. However, some patients never have their …

Objectives: To assess the relationship between microcirculatory perfusion and multiple
organ dysfunction syndrome in patients following traumatic hemorrhagic shock. Design …