User profiles for "author:E Macintyre"

Elizabeth Macintyre

Professor of Hematology
Verified email at aphp.fr
Cited by 39252

Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect …

JJM Van Dongen, AW Langerak, M Brüggemann… - Leukemia, 2003 - nature.com
In a European BIOMED-2 collaborative study, multiplex PCR assays have successfully been
developed and standardized for the detection of clonally rearranged immunoglobulin (Ig) …

Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease

JJM Van Dongen, EA Macintyre, JA Gabert… - Leukemia, 1999 - nature.com
Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia
patients have shown that large-scale MRD studies are feasible and that clinically relevant …

[HTML][HTML] EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations

AW Langerak, PJTA Groenen, M Brüggemann… - Leukemia, 2012 - nature.com
Abstract PCR-based immunoglobulin (Ig)/T-cell receptor (TCR) clonality testing in suspected
lymphoproliferations has largely been standardized and has consequently become …

LMO2-Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

…, F Gross, F Valensi, E Delabesse, E Macintyre… - science, 2003 - science.org
We have previously shown correction of X-linked severe combined immunodeficiency [SCID-
X1, also known as γ chain (γc) deficiency] in 9 out of 10 patients by retrovirus-mediated γc …

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data

…, MLC Loh, B Löwenberg, E Macintyre… - Blood, The Journal …, 2022 - ashpublications.org
The classification of myeloid neoplasms and acute leukemias was last updated in 2016
within a collaboration between the World Health Organization (WHO), the Society for …

The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee

…, MV Mateos, E Macintyre… - Blood, The Journal …, 2022 - ashpublications.org
Since the publication of the Revised European-American Classification of Lymphoid
Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have …

Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time'quantitative reverse-transcriptase polymerase …

…, R Dee, E van der Schoot, E Delabesse, E Macintyre… - Leukemia, 2003 - nature.com
Real-time quantitative RT-PCR (RQ-PCR) is a sensitive tool to monitor minimal residual
disease (MRD) in leukemic patients through the amplification of a fusion gene (FG) …

[HTML][HTML] EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes

…, M Cullen, AW Langerak, A Mendonça, E Macintyre… - Leukemia, 2012 - nature.com
Most consensus leukemia & lymphoma antibody panels consist of lists of markers based on
expert opinions, but they have not been validated. Here we present the validated EuroFlow …

Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma

…, N Patey, C Matuchansky, B Jabri, E Macintyre… - The Lancet, 2000 - thelancet.com
Background Adult refractory sprue is a poorly defined disorder. We did a multicentre national
study of patients with refractory sprue to characterise their clinical and pathological profile …

[PDF][PDF] Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia

…, D Bowen, S Killick, L Robinson, A Price, E Macintyre… - Cancer cell, 2011 - cell.com
The relationships between normal and leukemic stem/progenitor cells are unclear. We show
that in∼ 80% of primary human CD34+ acute myeloid leukemia (AML), two expanded …