Androgens exert important effects both in androgen-responsive tissues and in the intestinal
tract. To determine the impact of the gut microbiota (GM) on intestinal androgen metabolism …

Despite progress in the field of decellularization and recellularization, the outcome for
pancreas has not been adequate. This might be due to the challenging dual nature of …

Objective Food intake normally stimulates release of satiety and insulin-stimulating intestinal
hormones, such as glucagon-like peptide (GLP)-1. This response is blunted in obese insulin …

Tissue engineering of the whole pancreas can improve current treatments for diabetes
mellitus. The ultimate goal is to tissue engineer pancreas from an allogeneic or xenogeneic …

The angiotensin II type 2 receptor (AT 2) is upregulated after tissue damage and mediates
protective functions in the renin-angiotensin-aldosterone system (RAAS). One of these is to …

Background and aims: Insights into the nature of gut adaptation after different diets enhance
the understanding of how food modifications can be used to treat type 2 diabetes and …

Ingestion of nutrients stimulates incretin secretion from the enteroendocrine cells (EECs) of
the epithelial layer of the gut. Glucagon-like peptide-1 (GLP-1) is one of these incretins that …

Granular study of metabolic responses to alterations in the ratio of dietary macro-nutrients
can enhance our understanding of how dietary modifications influence patients with …

Background and aims: The conditions for jejunal glucose absorption in healthy subjects
have not been thoroughly studied. In this study we investigated differences in the jejunal villi …

Background: The prevalence of obesity and type-2 diabetes mellitus (T2DM) have risen
dramatically over the last decades, and are major threats to the human health. Obesity, and …