[HTML][HTML] Testing for ROS1 in non-small cell lung cancer: a review with recommendations
L Bubendorf, R Büttner, F Al-Dayel, M Dietel… - Virchows Archiv, 2016 - Springer
Rearrangements of the ROS1 gene occur in 1–2% of non-small cell lung cancers (NSCLCs).
Crizotinib, a highly effective inhibitor of ROS1 kinase activity, is now FDA-approved for the …
Crizotinib, a highly effective inhibitor of ROS1 kinase activity, is now FDA-approved for the …
Role of phosphatidylinositol 3′-kinase/AKT pathway in diffuse large B-cell lymphoma survival
S Uddin, AR Hussain, AK Siraj, PS Manogaran… - Blood, 2006 - ashpublications.org
Abstract Phosphatidylinositol 3′-kinase (PI3K) is a key player in cell-growth signaling in a
number of lymphoid malignancies, but its role in diffuse large B-cell lymphoma (DLBCL) has …
number of lymphoid malignancies, but its role in diffuse large B-cell lymphoma (DLBCL) has …
Clinicopathological Analysis of Papillary Thyroid Cancer with PIK3CA Alterations in a Middle Eastern Population
Context: Genetic aberration in phosphatidylinositol 3-kinase (PI3K)/AKT pathway has been
detected in numerous and diverse human cancers. PIK3CA, which encodes for the catalytic …
detected in numerous and diverse human cancers. PIK3CA, which encodes for the catalytic …
[HTML][HTML] Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy
To identify genes potentially playing an important role in the progression of colorectal
carcinoma (CRC), we screened global gene expression using cDNA expression array on 41 …
carcinoma (CRC), we screened global gene expression using cDNA expression array on 41 …
Clinical significance of Blastocystis hominis
SM Qadri, GA al-Okaili, F al-Dayel - Journal of Clinical …, 1989 - Am Soc Microbiol
A total of 19,252 stool specimens from 12,136 patients were examined by direct microscopy
and the ethyl acetate-Formalin concentration method during the last 2 years. All liquid …
and the ethyl acetate-Formalin concentration method during the last 2 years. All liquid …
[HTML][HTML] Overexpression of leptin receptor predicts an unfavorable outcome in Middle Eastern ovarian cancer
S Uddin, R Bu, M Ahmed, J Abubaker, F Al-Dayel… - Molecular cancer, 2009 - Springer
Background Recent epidemiological studies have suggested that obesity is associated with
ovarian cancer. Obesity hormone leptin and its receptor (Ob-R) contribute to tumor …
ovarian cancer. Obesity hormone leptin and its receptor (Ob-R) contribute to tumor …
HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer
K Al-Kuraya, H Novotny, P Bavi, AK Siraj… - Journal of clinical …, 2007 - jcp.bmj.com
Aim: Recent studies had suggested substantial molecular differences between tumours from
different ethnic groups. In this study, the molecular differences between the incidences of …
different ethnic groups. In this study, the molecular differences between the incidences of …
Cyclooxygenase‐2 inhibition inhibits PI3K/AKT kinase activity in epithelial ovarian cancer
Abstract Cyclooxygenase‐2 (COX‐2) expression contributes to tumor growth and invasion in
epithelial ovarian cancer (EOC). COX‐2 inhibitors exhibit important anticarcinogenic …
epithelial ovarian cancer (EOC). COX‐2 inhibitors exhibit important anticarcinogenic …
PIK3CA mutations are mutually exclusive with PTEN loss in diffuse large B-cell lymphoma
J Abubaker, PP Bavi, S Al-Harbi, AK Siraj, F Al-Dayel… - Leukemia, 2007 - nature.com
Dr S Siitonen is acknowledged for the valuable help with the flow cytometry and the
laboratory technicians in the Laboratory of Hematology, HUSLAB are acknowledged for their …
laboratory technicians in the Laboratory of Hematology, HUSLAB are acknowledged for their …
Leptin-R and its association with PI3K/AKT signaling pathway in papillary thyroid carcinoma
The putative role of leptin and its receptor (Ob-R) in the pathogenesis of various primary
human malignancies has been reported; however, their role in papillary thyroid cancer …
human malignancies has been reported; however, their role in papillary thyroid cancer …