Antidepressant-induced liver injury: a review for clinicians

…, E Corruble, S Naveau, G Perlemuter - American Journal of …, 2014 - Am Psychiatric Assoc
Objective Antidepressant drugs can cause drug-induced liver injury (DILI). The authors
review clinical data relevant to antidepressant-induced liver injury and provide …

Hepatitis C virus particles and lipoprotein metabolism

P André, G Perlemuter, A Budkowska… - Seminars in liver …, 2005 - thieme-connect.com
The majority of infectious hepatitis C particles are present in the low-density fractions from
plasma of infected patients, suggesting an association of the virus with lipoproteins and the …

Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral‐related steatosis

G Perlemuter, A Sabile, P Letteron, G Vona… - The FASEB …, 2002 - Wiley Online Library
Liver steatosis, which involves accumulation of intracytoplasmic lipid droplets, is
characteristic of hepatitis C virus (HCV) infection. By use of an in vivo transgenic murine …

Drug insight: gastrointestinal and hepatic adverse effects of molecular-targeted agents in cancer therapy

Y Loriot, G Perlemuter, D Malka… - Nature clinical practice …, 2008 - nature.com
Recent advances in the understanding of molecular mechanisms of cancer have led to the
development of novel compounds that target specific cancer pathways. These drugs …

Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease

…, C Jousse, S Naveau, P Gérard, G Perlemuter - Gut, 2016 - gut.bmj.com
Objective There is substantial inter-individual diversity in the susceptibility of alcoholics to
liver injury. Alterations of intestinal microbiota (IM) have been reported in alcoholic liver …

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

…, P Martin, C Philippe, F Walker, A Bado, G Perlemuter… - Gut, 2013 - gut.bmj.com
Objective Non-alcoholic fatty liver disease (NAFLD) is prevalent among obese people and is
considered the hepatic manifestation of metabolic syndrome. However, not all obese …

High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic …

V Paradis, G Perlemuter, F Bonvoust, D Dargere… - Hepatology, 2001 - Elsevier
Nonalcoholic steatohepatitis (NASH) may progress to liver fibrosis and cirrhosis.
Mechanisms directly involved in the development of fibrosis have been poorly investigated …

Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liver disease

…, L Mayr, M Drach, P Moser, AR Moschen, G Perlemuter… - Gut, 2018 - gut.bmj.com
Objective Alcoholic liver disease (ALD) is a global health problem with limited therapeutic
options. Intestinal barrier integrity and the microbiota modulate susceptibility to ALD …

[PDF][PDF] Diagnostic and prognostic values of noninvasive biomarkers of fibrosis in patients with alcoholic liver disease

…, A Balian, M Njiké‐Nakseu, G Perlemuter… - …, 2009 - Wiley Online Library
FibroTest has been validated as a biomarker of fibrosis in patients with chronic viral
hepatitis, with a similar prognostic value as biopsy. The aim of the study was to compare the …

Fecal microbiota manipulation prevents dysbiosis and alcohol-induced liver injury in mice

…, D Berrebi, M Thomas, S Naveau, G Perlemuter… - Journal of …, 2017 - Elsevier
Background & Aims Alcoholic liver disease (ALD) is a leading cause of liver failure and
mortality. In humans, severe alcoholic hepatitis is associated with key changes to intestinal …