User profiles for "author:Georg Zeller"

Georg Zeller

EMBL, Heidelberg
Verified email at embl.de
Cited by 28720

Enterotypes in the landscape of gut microbial community composition

PI Costea, F Hildebrand, M Arumugam, F Bäckhed… - Nature …, 2018 - nature.com
Population stratification is a useful approach for a better understanding of complex
biological problems in human health and wellbeing. The proposal that such stratification …

[HTML][HTML] Reporting guidelines for human microbiome research: the STORMS checklist

C Mirzayi, A Renson… - Nature medicine, 2021 - nature.com
The particularly interdisciplinary nature of human microbiome research makes the
organization and reporting of results spanning epidemiology, biology, bioinformatics …

Structure and function of the global ocean microbiome

S Sunagawa, LP Coelho, S Chaffron, JR Kultima… - Science, 2015 - science.org
Microbes are dominant drivers of biogeochemical processes, yet drawing a global picture of
functional diversity, microbial community structure, and their ecological determinants …

Extensive impact of non-antibiotic drugs on human gut bacteria

L Maier, M Pruteanu, M Kuhn, G Zeller, A Telzerow… - Nature, 2018 - nature.com
A few commonly used non-antibiotic drugs have recently been associated with changes in
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …

Drug discovery in the age of systems biology: the rise of computational approaches for data integration

M Iskar, G Zeller, XM Zhao, V van Noort… - Current opinion in …, 2012 - Elsevier
The increased availability of large-scale open-access resources on bioactivities of small
molecules has a significant impact on pharmacology facilitated mainly by computational …

Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project

MB Gerstein, ZJ Lu, EL Van Nostrand, C Cheng… - Science, 2010 - science.org
We systematically generated large-scale data sets to improve genome annotation for the
nematode Caenorhabditis elegans, a key model organism. These data sets include …

Potential of fecal microbiota for early‐stage detection of colorectal cancer

G Zeller, J Tap, AY Voigt, S Sunagawa… - Molecular systems …, 2014 - embopress.org
Several bacterial species have been implicated in the development of colorectal carcinoma
(CRC), but CRC‐associated changes of fecal microbiota and their potential for cancer …

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

J Wirbel, PT Pyl, E Kartal, K Zych, A Kashani… - Nature medicine, 2019 - nature.com
Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …

Common Sequence Polymorphisms Shaping Genetic Diversity in Arabidopsis thaliana

RM Clark, G Schweikert, C Toomajian, S Ossowski… - science, 2007 - science.org
The genomes of individuals from the same species vary in sequence as a result of different
evolutionary processes. To examine the patterns of, and the forces shaping, sequence …

Towards standards for human fecal sample processing in metagenomic studies

PI Costea, G Zeller, S Sunagawa, E Pelletier… - Nature …, 2017 - nature.com
Technical variation in metagenomic analysis must be minimized to confidently assess the
contributions of microbiota to human health. Here we tested 21 representative DNA …