Gut microbiota modulate T cell trafficking into human colorectal cancer

E Cremonesi, V Governa, JFG Garzon, V Mele… - Gut, 2018 - gut.bmj.com
Objective Tumour-infiltrating lymphocytes (TILs) favour survival in human colorectal cancer
(CRC). Chemotactic factors underlying their recruitment remain undefined. We investigated …

Disseminated single tumor cells as detected by real-time quantitative polymerase chain reaction represent a prognostic factor in patients undergoing surgery for …

U Guller, P Zajac, A Schnider, B Bösch… - Annals of …, 2002 - journals.lww.com
Objective To evaluate the clinical relevance of real-time quantitative polymerase chain
reaction (qPCR) detection of CEA and CK20 transcripts, as potentially related to tumor cell …

HLA class II antigen expression in colorectal carcinoma tumors as a favorable prognostic marker

G Sconocchia, S Eppenberger-Castori, I Zlobec… - Neoplasia, 2014 - Elsevier
The goal of this study was to determine the frequency of HLA class II antigen expression in
colorectal carcinoma (CRC) tumors, its association with the clinical course of the disease …

CD133+, CD166+ CD44+, and CD24+ CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human …

MG Muraro, V Mele, S Däster, J Han… - Stem cells …, 2012 - academic.oup.com
Increasing evidence that cancers originate from small populations of so-called cancer stem
cells (CSCs), capable of surviving conventional chemotherapies and regenerating the …

Defective infiltration of natural killer cells in MICA/B-positive renal cell carcinoma involves β2-integrin-mediated interaction

G Sconocchia, GC Spagnoli, D Del Principe, S Ferrone… - Neoplasia, 2009 - Elsevier
We have explored MICA/B expression and its relationship with innate inflammatory infiltrate
in renal cell carcinoma (RCC). The expression of MICA/B, CD16, CD56, and CD68 in 140 …

Expression of cancer‐testis antigens MAGE‐A4 and MAGE‐C1 in oral squamous cell carcinoma

JRMC Montoro, RCM Mamede, L Neder Serafini… - Head & …, 2012 - Wiley Online Library
Background Tumor markers are genes or their products expressed exclusively or
preferentially in tumor cells and cancer‐testis antigens (CTAs) form a group of genes with a …

Immunohistochemical expression of tumor antigens MAGE‐A1, MAGE‐A3/4, and NY‐ESO‐1 in cancerous and benign prostatic tissue

T Hudolin, A Juretic, GC Spagnoli, J Pasini… - The …, 2006 - Wiley Online Library
OBJECTIVE To investigate immunohistochemical expression of MAGE‐A and NY‐ESO‐
1/LAGE‐1, cancer testis antigens in prostate tissues showing evidence of malignant …

[HTML][HTML] Prognostic significance of lymphocyte infiltrate localization in triple-negative breast cancer

T Čeprnja, I Mrklić, M Perić Balja, Z Marušić… - Journal of personalized …, 2022 - mdpi.com
High infiltration by tumor-infiltrating lymphocytes (TILs) is associated with favorable
prognosis in different tumor types, but the clinical significance of their spatial localization …

[HTML][HTML] Local activation of the innate immune system in Buruli ulcer lesions

E Peduzzi, C Groeper, D Schütte, P Zajac… - Journal of investigative …, 2007 - Elsevier
Buruli ulcer (BU) caused by Mycobacterium ulcerans is a chronic necrotizing disease of the
skin and the underlying soft tissue. Fat tissue necrosis accompanied by minimal …

Co-expression of cancer testis antigens and topoisomerase 2-alpha in triple negative breast carcinomas

I Mrklić, GC Spagnoli, A Juretić, Z Pogorelić, S Tomić - Acta histochemica, 2014 - Elsevier
Triple negative breast cancers (TNBC) are characterized by aggressive tumor biology, lack
of targeted treatments and poor prognosis. Anthracyclins were shown to induce …