User profiles for "author:Gregory Da Costa"

Grégory Da Costa

Associate professor Université de Bordeaux
Verified email at u-bordeaux.fr
Cited by 1590

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

B Lamas, ML Richard, V Leducq, HP Pham… - Nature medicine, 2016 - nature.com
Complex interactions between the host and the gut microbiota govern intestinal homeostasis
but remain poorly understood. Here we reveal a relationship between gut microbiota and …

[PDF][PDF] Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome

JM Natividad, A Agus, J Planchais, B Lamas, AC Jarry… - Cell metabolism, 2018 - cell.com
The extent to which microbiota alterations define or influence the outcome of metabolic
diseases is still unclear, but the byproducts of microbiota metabolism are known to have an …

[HTML][HTML] Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice

JM Natividad, B Lamas, HP Pham, ML Michel… - Nature …, 2018 - nature.com
Dietary lipids favor the growth of the pathobiont Bilophila wadsworthia, but the relevance of
this expansion in metabolic syndrome pathogenesis is poorly understood. Here, we showed …

[PDF][PDF] Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells

L Dupraz, A Magniez, N Rolhion, ML Richard… - Cell Reports, 2021 - cell.com
Summary Gut interleukin-17A (IL-17)-producing γδ T cells are tissue-resident cells that are
involved in both host defense and regulation of intestinal inflammation. However, factors that …

Fungal dysbiosis in mucosa-associated microbiota of Crohn's disease patients

G Liguori, B Lamas, ML Richard… - Journal of Crohn's …, 2016 - academic.oup.com
Abstract Background and Aims: Gut microbiota is involved in many physiological functions
and its imbalance is associated with several diseases, particularly with inflammatory bowel …

[HTML][HTML] Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity

A Plaine, L Walker, G Da Costa… - Fungal Genetics and …, 2008 - Elsevier
The outer layer of the Candida albicans cell wall is enriched in highly glycosylated proteins.
The major class, the GlycosylPhosphatidylInositol (GPI)-anchored proteins are tethered to …

Mucosa-associated microbiota dysbiosis in colitis associated cancer

ML Richard, G Liguori, B Lamas, G Brandi… - Gut …, 2018 - Taylor & Francis
Gut microbiota dysbiosis has been associated with inflammatory bowel diseases (IBD). In
colorectal cancer, the gut microbiota has also been recognized as potentially involved in …

[HTML][HTML] Enterobacteriaceae are essential for the modulation of colitis severity by fungi

B Sovran, J Planchais, S Jegou, M Straube, B Lamas… - Microbiome, 2018 - Springer
Background Host-microbe balance maintains intestinal homeostasis and strongly influences
inflammatory conditions such as inflammatory bowel diseases (IBD). Here we focused on …

Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases

C Michaudel, C Danne, A Agus, A Magniez… - Gut, 2023 - gut.bmj.com
Objective The extent to which tryptophan (Trp) metabolism alterations explain or influence
the outcome of inflammatory bowel diseases (IBDs) is still unclear. However, several Trp …

Phenolic contents and bioactive potential of peach fruit extracts

A Mokrani, S Krisa, S Cluzet, G Da Costa… - Food Chemistry, 2016 - Elsevier
Several cultivars of peach fruit (Prunus persica L.) were investigated. Their phenolic
composition and concentration were assessed by LC–MS. Concentrations were calculated …