Objective To establish the non-inferior efficacy of vonoprazan versus lansoprazole in the
treatment of Asian patients with erosive oesophagitis (EO). Design In this phase III, double …

Methods The rat model was induced by heterotypic chronic and acute stress (CAS). The
intestinal transit was measured by administering powdered carbon by gastric gavage …

Intestinal‐type gastric cancer (IGC) has a clear and multistep histological evolution. No
studies have comprehensively explored gastric tumorigenesis from inflammation through …

Lubiprostone activates ClC-2 chloride channels in epithelia. It is approved for treatment of
chronic idiopathic constipation in adults and constipation-predominate irritable bowel …

Background Treatment of irritable bowel syndrome (IBS) with probiotics has achieved
effectiveness to a certain extent. Whether prebiotics will work is still unclear. This study …

Serotonin [5-hydroxytryptamine (5-HT)] is released from enterochromaffin cells in the
mucosa of the small intestine. We tested a hypothesis that elevation of 5-HT in the …

Background Immune factors were involved in the pathophysiology of irritable bowel
syndrome (IBS). The aim of the study was to test anti‐neuronal antibodies in sera of IBS …

Clinical characteristics of cytomegalovirus gastritis: A ret... : Medicine Clinical characteristics of
cytomegalovirus gastritis: A retrospective study from a tertiary medical center : Medicine Log …

Abstract Background In Asia, the proportion of patients with irritable bowel syndrome (IBS)
with abdominal discomfort alone is significantly higher than that in western countries. The …

Actions of lubiprostone, a selective type-2 chloride channel activator, on mucosal secretion
were investigated in guinea pig small intestine and colon. Flat-sheet preparations were …