[HTML][HTML] GM-CSF grown bone marrow derived cells are composed of phenotypically different dendritic cells and macrophages
Granulocyte-macrophage colony stimulating factor (GM-CSF) has a role in inducing
emergency hematopoiesis upon exposure to inflammatory stimuli. Although GM-CSF …
emergency hematopoiesis upon exposure to inflammatory stimuli. Although GM-CSF …
Prostaglandin E2 receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation
YR Na, D Jung, M Stakenborg, H Jang, GJ Gu… - Gut, 2021 - gut.bmj.com
Objective Dysfunctional resolution of intestinal inflammation and altered mucosal healing
are essential features in the pathogenesis of inflammatory bowel disease (IBD). Intestinal …
are essential features in the pathogenesis of inflammatory bowel disease (IBD). Intestinal …
[HTML][HTML] Mannosylated-serum albumin nanoparticle imaging to monitor tumor-associated macrophages under anti-PD1 treatment
Background Immune checkpoint inhibitors such as anti-programmed cell death protein 1
(PD1) block tumor growth by reinvigorating the immune system; however, determining their …
(PD1) block tumor growth by reinvigorating the immune system; however, determining their …
Circulation time-optimized albumin nanoplatform for quantitative visualization of lung metastasis via targeting of macrophages
The development of molecular imaging probes to identify key cellular changes within lung
metastases may lead to noninvasive detection of metastatic lesions in the lung. In this study …
metastases may lead to noninvasive detection of metastatic lesions in the lung. In this study …
Peucedanum japonicum extract attenuates allergic airway inflammation by inhibiting Th2 cell activation and production of pro-inflammatory mediators
JM Chun, AR Lee, HS Kim, AY Lee, GJ Gu… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance The root of Peucedanum japonicum Thunberg is
traditionally used to treat coughs, colds, headache and inflammatory diseases in Korea and …
traditionally used to treat coughs, colds, headache and inflammatory diseases in Korea and …
Reduced allergic lung inflammation by root extracts from two species of Peucedanum through inhibition of Th2 cell activation
AR Lee, JM Chun, AY Lee, HS Kim, GJ Gu… - Journal of …, 2017 - Elsevier
Abstract Ethnopharmacological evidence Peucedani Radix (PR), the root of Peucedanum
praeruptorum Dunn (PPD) or Peucedanum decursivum (Miq.) Maxim.(PDM), has long been …
praeruptorum Dunn (PPD) or Peucedanum decursivum (Miq.) Maxim.(PDM), has long been …
The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production
Interleukin-10 (IL-10) is an important anti-inflammatory cytokine that is produced primarily by
macrophages. We investigated mechanisms by which the timing of IL-10 production was …
macrophages. We investigated mechanisms by which the timing of IL-10 production was …
[HTML][HTML] Consistent inhibition of cyclooxygenase drives macrophages towards the inflammatory phenotype
Macrophages play important roles in defense against infection, as well as in homeostasis
maintenance. Thus alterations of macrophage function can have unexpected pathological …
maintenance. Thus alterations of macrophage function can have unexpected pathological …
Phenethyl isothiocyanate regulates inflammation through suppression of the TRIF-dependent signaling pathway of Toll-like receptors
HJ Park, SJ Kim, SJ Park, SH Eom, GJ Gu, SH Kim… - Life sciences, 2013 - Elsevier
AIMS: The aim of this study was to evaluate the therapeutic potential of the phenethyl
isothiocyanate (PEITC) in Toll-like receptor (TLR) signaling pathways. MAIN METHODS: To …
isothiocyanate (PEITC) in Toll-like receptor (TLR) signaling pathways. MAIN METHODS: To …
[HTML][HTML] Fasiglifam (TAK-875), a G protein-coupled receptor 40 (GPR40) agonist, may induce hepatotoxicity through reactive oxygen species generation in a GPR40 …
MJ Kim, GJ Gu, YS Koh, SH Lee, YR Na… - Biomolecules & …, 2018 - ncbi.nlm.nih.gov
Abstract Fasiglifam (TAK-875) a G-protein coupled receptor 40 (GPR40) agonist,
significantly improves hyperglycemia without hypoglycemia and weight gain, the major side …
significantly improves hyperglycemia without hypoglycemia and weight gain, the major side …