Background Studies have shown associations between mortality and long-term exposure to
particulate matter air pollution. Few cohort studies have estimated the effects of the …

Background: Long-term exposure to air pollution has been hypothesized to elevate arterial
blood pressure (BP). The existing evidence is scarce and country specific. Objectives: We …

Lung cancer is the most common cause of cancer death worldwide, with over one million
cases annually. To identify genetic factors that modify disease risk, we conducted a genome …

Background Dietary fibre is thought to protect against colorectal cancer but this view has
been challenged by recent prospective and intervention studies that showed no protective …

Background: Current evidence suggests that high red meat intake is associated with
increased colorectal cancer risk. High fish intake may be associated with a decreased risk …

We conducted a two-stage genome-wide association study of pancreatic cancer, a cancer
with one of the lowest survival rates worldwide. We genotyped 558,542 SNPs in 1,896 …

The evidence for anthropometric factors influencing breast cancer risk is accumulating, but
uncertainties remain concerning the role of fat distribution and potential effect modifiers. We …

Background: Body weight and body mass index (BMI) are positively related to risk of colon
cancer in men, whereas weak or no associations exist in women. This discrepancy may be …

We conducted a genome-wide association study of pancreatic cancer in 3,851 affected
individuals (cases) and 3,934 unaffected controls drawn from 12 prospective cohort studies …

In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-
wide association studies, we observed large chromosomal abnormalities in a subset of …