[PDF][PDF] Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia

N Goardon, E Marchi, A Atzberger, L Quek, A Schuh… - Cancer cell, 2011 - cell.com
The relationships between normal and leukemic stem/progenitor cells are unclear. We show
that in∼ 80% of primary human CD34+ acute myeloid leukemia (AML), two expanded …

Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial

P Moreau, MA Dimopoulos, J Mikhael, K Yong… - The Lancet, 2021 - thelancet.com
Background Isatuximab is an anti-CD38 monoclonal antibody approved in combination with
pomalidomide–dexamethasone and carfilzomib–dexamethasone for relapsed or refractory …

Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a …

PG Richardson, A Oriol, M Beksac, AM Liberati… - The Lancet …, 2019 - thelancet.com
Background As lenalidomide becomes increasingly established for upfront treatment of
multiple myeloma, patients refractory to this drug represent a population with an unmet …

UK consensus statement on the use of plerixafor to facilitate autologous peripheral blood stem cell collection to support high‐dose chemoradiotherapy for patients with …

KW Douglas, M Gilleece, P Hayden… - Journal of clinical …, 2018 - Wiley Online Library
Plerixafor is a CXC chemokine receptor (CXCR4) antagonist that mobilizes stem cells in the
peripheral blood. It is indicated (in combination with granulocyte‐colony stimulating factor [G …

Food avoidance strategies in eosinophilic oesophagitis

A Cianferoni, M Shuker… - Clinical & …, 2019 - Wiley Online Library
Eosinophilic oesophagitis (EoE) is a chronic disease associated with significant morbidity
that can result in permanent fibrosis and stricture formation. Given the complexity, a …

Genetically distinct leukemic stem cells in human CD34 acute myeloid leukemia are arrested at a hemopoietic precursor-like stage

L Quek, GW Otto, C Garnett, L Lhermitte… - Journal of Experimental …, 2016 - rupress.org
Our understanding of the perturbation of normal cellular differentiation hierarchies to create
tumor-propagating stem cell populations is incomplete. In human acute myeloid leukemia …

The effect of salvage autologous stem-cell transplantation on overall survival in patients with relapsed multiple myeloma (final results from BSBMT/UKMF Myeloma X …

G Cook, AJ Ashcroft, DA Cairns, CD Williams… - The Lancet …, 2016 - thelancet.com
Summary Background The Myeloma X trial previously reported improved durability of
response (time to disease progression) in patients with relapsed multiple myeloma with …

British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines on the …

A Dhar, HN Haboubi, SE Attwood, MKH Auth, JM Dunn… - Gut, 2022 - gut.bmj.com
Background Eosinophilic oesophagitis (EoE) is an increasingly common cause of dysphagia
in both children and adults, as well as one of the most prevalent oesophageal diseases with …

Updated outcomes and impact of age with lenalidomide and low-dose dexamethasone or melphalan, prednisone, and thalidomide in the randomized, phase III FIRST …

C Hulin, A Belch, C Shustik, MT Petrucci… - Journal of Clinical …, 2016 - biblio.ugent.be
Purpose: This analysis of the FIRST trial in patients with newly diagnosed multiple myeloma
(MM) ineligible for stem-cell transplantation examined updated outcomes and impact of …

An Integrative Model of Youth Anxiety: Cognitive-Affective Processes and Parenting in Developmental Context

KB Allen, PZ Tan, JA Sullivan, M Baumgardner… - Clinical Child and …, 2023 - Springer
Multiple theoretical frameworks have been proposed to provide a more comprehensive
picture of the risk factors that influence anxiety-related developmental trajectories …