Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites

X Zhang, OO Coker, ESH Chu, K Fu, HCH Lau… - Gut, 2021 - gut.bmj.com
Objective Non-alcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma
(HCC) is an increasing healthcare burden worldwide. We examined the role of dietary …

Bone marrow‐derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells

J Han, X Zhang, JKC Lau, K Fu, HCH Lau… - The Journal of …, 2019 - Wiley Online Library
The role of macrophages in fibrosing steatohepatitis is largely unclear. We characterized the
origin and molecular mechanisms of macrophages and its targeted therapy of fibrosing …

[HTML][HTML] High soluble fiber promotes colorectal tumorigenesis through modulating gut microbiota and metabolites in mice

J Yang, H Wei, Y Lin, ESH Chu, Y Zhou, H Gou, S Guo… - Gastroenterology, 2024 - Elsevier
Background & Aims Dietary fibers are mainly fermented by the gut microbiota, but their roles
in colorectal cancer (CRC) are largely unclear. Here, we investigated the associations of …

[HTML][HTML] Bile acids, gut microbiota, and therapeutic insights in hepatocellular carcinoma

Y Song, HCH Lau, X Zhang, J Yu - Cancer Biology & Medicine, 2024 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a prevalent and aggressive liver malignancy. The
interplay between bile acids (BAs) and the gut microbiota has emerged as a critical factor in …

Paper Alert A selection of interesting papers that were published in the month before our press date in major journals likely to report important results in …

HSFP Colorectal, J Yang, H Wei, Y Lin… - European Journal of …, 2024 - journals.lww.com
Paper Alert : European Journal of Gastroenterology & Hepatology Paper Alert : European
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