A simple diet-and chemical-induced murine NASH model with rapid progression of steatohepatitis, fibrosis and liver cancer
T Tsuchida, YA Lee, N Fujiwara, M Ybanez, B Allen… - Journal of …, 2018 - Elsevier
Background and Aims Although the majority of patients with non-alcoholic fatty liver disease
(NAFLD) have only steatosis without progression, a sizeable fraction develop non-alcoholic …
(NAFLD) have only steatosis without progression, a sizeable fraction develop non-alcoholic …
Attendance of board meetings and company performance: Evidence from Taiwan
This paper empirically investigates board meeting attendance and its effects on the
performance of Taiwanese listed corporations. Directors with higher qualifications attend …
performance of Taiwanese listed corporations. Directors with higher qualifications attend …
[HTML][HTML] Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap
Activation of the Hippo pathway effector Yap underlies many liver cancers, however no
germline or somatic mutations have been identified. Autophagy maintains essential …
germline or somatic mutations have been identified. Autophagy maintains essential …
A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection
DY Zhang, N Goossens, J Guo, MC Tsai, HI Chou… - Gut, 2016 - gut.bmj.com
Objective We used an informatics approach to identify and validate genes whose expression
is unique to hepatic stellate cells and assessed the prognostic capability of their expression …
is unique to hepatic stellate cells and assessed the prognostic capability of their expression …
[HTML][HTML] The XBP1 arm of the unfolded protein response induces fibrogenic activity in hepatic stellate cells through autophagy
RS Kim, D Hasegawa, N Goossens, T Tsuchida… - Scientific reports, 2016 - nature.com
Autophagy and the unfolded protein response (UPR) both promote activation of hepatic
stellate cells (HSC), however the link between the two stimuli remains unclear. Here we …
stellate cells (HSC), however the link between the two stimuli remains unclear. Here we …
The effects of financial distress and capital structure on the work effort of outside directors
This paper investigates the conflict of interests between shareholders and debtholders by
examining the work effort of outside directors when a company experiences financial …
examining the work effort of outside directors when a company experiences financial …
Innovation or dividend payout: Evidence from China
B Yang, HI Chou, J Zhao - International Review of Economics & Finance, 2020 - Elsevier
Abstract Since 2001, the China Securities Regulatory Commission has implemented a
series of policies to ensure that dividend payments constitute a prerequisite of equity …
series of policies to ensure that dividend payments constitute a prerequisite of equity …
Epithelial Xbp1 is required for cellular proliferation and differentiation during mammary gland development
D Hasegawa, V Calvo, A Avivar-Valderas… - … and cellular biology, 2015 - Taylor & Francis
Xbp1, a key mediator of the unfolded protein response (UPR), is activated by IRE1α-
mediated splicing, which results in a frameshift to encode a protein with transcriptional …
mediated splicing, which results in a frameshift to encode a protein with transcriptional …
Anti‐fibrotic activity and enhanced interleukin‐6 production by hepatic stellate cells in response to imatinib mesylate
Y Kim, MI Fiel, E Albanis, HI Chou, W Zhang… - Liver …, 2012 - Wiley Online Library
Objective To examine imatinib mesylate's effects on stellate cell responses in vivo and in
vitro. The hepatic stellate cell (HSC) is a key target of anti‐fibrotic therapies. Imatinib …
vitro. The hepatic stellate cell (HSC) is a key target of anti‐fibrotic therapies. Imatinib …
Are all regulatory compliant independent director appointments the same? An analysis of Taiwanese board appointments
HI Chou, PA Hamill, YH Yeh - Journal of Corporate Finance, 2018 - Elsevier
Globally many regulators adopted a rules-based approach to independent director
appointments stipulating 'independence'criteria. This paper investigates whether partitioning …
appointments stipulating 'independence'criteria. This paper investigates whether partitioning …